Sodium Orthovanadate Changes Fatty Acid Composition and Increased Expression of Stearoyl-Coenzyme A Desaturase in THP-1 Macrophages
Sign Up to like & getrecommendations! Published in 2019 at "Biological Trace Element Research"
DOI: 10.1007/s12011-019-01699-2
Abstract: Vanadium compounds are promising antidiabetic agents. In addition to regulating glucose metabolism, they also alter lipid metabolism. Due to the clear association between diabetes and atherosclerosis, the purpose of the present study was to assess… read more here.
Keywords: acid; expression; sodium orthovanadate; desaturase ... See more keywords
Evaluation of sodium orthovanadate as a radioprotective agent under total-body irradiation and partial-body irradiation conditions in mice
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Radiation Biology"
DOI: 10.1080/09553002.2021.1941377
Abstract: Abstract Purpose Our previous study indicated that sodium orthovanadate (vanadate), a strong inhibitor of p53, effectively suppressed the lethality from the hematopoietic (HP) and gastrointestinal (GI) syndromes after 12 Gy total-body irradiation (TBI) in mice. This… read more here.
Keywords: total body; body irradiation; irradiation partial; sodium orthovanadate ... See more keywords
Is there a Role for Sodium Orthovanadate in the Treatment of Diabetes?
Sign Up to like & getrecommendations! Published in 2019 at "Current diabetes reviews"
DOI: 10.2174/1573399814666180903162556
Abstract: BACKGROUND Diabetes is a metabolic disorder, whose incidences are increasing day by day. Various classes of anti-diabetic drugs are clinically approved by the Food and Drug Administration (FDA) for the treatment of diabetes mellitus, but… read more here.
Keywords: role; treatment diabetes; sodium orthovanadate; sodium ... See more keywords
p38-dependent c-Jun degradation contributes to reduced PGE2 production in sodium orthovanadate-treated macrophages
Sign Up to like & getrecommendations! Published in 2022 at "BMB Reports"
DOI: 10.5483/bmbrep.2022.55.8.115
Abstract: In particular, the phenomenon of c-Jun degradation within the inflammatory response has not yet been fully analyzed. In order to verify this, we investigated LPS-stimulated murine macrophages pre-treated with sodium orthovanadate (SO) in order to… read more here.
Keywords: degradation; dependent jun; sodium orthovanadate; jun degradation ... See more keywords