Investigating the Influence of Excipients on the Stability of Levothyroxine Sodium Pentahydrate.
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DOI: 10.1021/acs.molpharmaceut.1c00217
Abstract: A range of tablet excipients were evaluated for their influence on the physical form and chemical stability of levothyroxine sodium pentahydrate (LSP; C15H10I4NNaO4ยท5H2O). LSP-excipient binary powder blends were stored under two conditions: (a) in hermetically… read more here.
Keywords: stability levothyroxine; sodium pentahydrate; sodium; stability ... See more keywords
New Insights on Solid-State Changes in the Levothyroxine Sodium Pentahydrate during Dehydration and its Relationship to Chemical Instability
Sign Up to like & getrecommendations! Published in 2018 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-018-1264-0
Abstract: Levothyroxine sodium pentahydrate (LEVO) tablets have been on the US market since the mid-twentieth century and remain the most highly prescribed product. Unfortunately, levothyroxine sodium tablets have also been one of the most highly recalled… read more here.
Keywords: solid state; chemical instability; sodium pentahydrate; sodium ... See more keywords