Sodium tanshinone IIA sulfonate protects ARPE-19 cells against oxidative stress by inhibiting autophagy and apoptosis
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DOI: 10.1038/s41598-018-33552-2
Abstract: Oxidative stress in retinal pigment epithelium (RPE) is considered to be a major contributor to the development and progression of age-related macular degeneration (AMD). Previous investigations have shown that sodium tanshinone IIA sulfonate (STS) can… read more here.
Keywords: arpe cells; cells oxidative; sodium tanshinone; apoptosis ... See more keywords
Sodium tanshinone IIA silate increases melanin synthesis by activating the MAPK and PKA pathways and protects melanocytes from H2O2-induced oxidative stress
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c8ra09786k
Abstract: Vitiligo is an intriguing depigmentation disorder that affects about 0.5–2% of the world population. read more here.
Keywords: sodium tanshinone; iia silate; increases melanin; tanshinone iia ... See more keywords
Relaxant Effect of Sodium Tanshinone IIA Sulphonate on Mouse Tracheal Smooth Muscle.
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DOI: 10.1055/s-0042-119950
Abstract: Sodium tanshinone IIA sulphonate, a water-soluble derivative of tanshinone IIA, has been proven to possess versatile biological properties, but its pharmacological effect on tracheal smooth muscle remains elusive. This paper presents a study on the… read more here.
Keywords: tanshinone; sodium tanshinone; iia sulphonate; tanshinone iia ... See more keywords
Sodium tanshinone IIA sulfonate protects against Aβ‐induced cell toxicity through regulating Aβ process
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DOI: 10.1111/jcmm.15006
Abstract: Sodium tanshinone IIA sulfonate (STS) has been reported to prevent Alzheimer's disease (AD). However, the mechanism is still unknown. In this study, two in vitro models, Aβ‐treated SH‐SY5Y cells and SH‐SY5Y human neuroblastoma cells transfected… read more here.
Keywords: iia sulfonate; sodium tanshinone; tanshinone iia;
Exploration of Multiple Signaling Pathways Through Which Sodium Tanshinone IIA Sulfonate Attenuates Pathologic Remodeling Experimental Infarction
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.00779
Abstract: The level of maladaptive myocardial remodeling consistently contributes to the poor prognosis of patients following a myocardial infarction (MI). In this study, we investigated whether and how sodium tanshinone IIA sulfonate (STS) would attenuate the… read more here.
Keywords: iia sulfonate; sodium tanshinone; tanshinone iia; infarction ... See more keywords