Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population
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DOI: 10.1080/07853890.2022.2096257
Abstract: Abstract Background Epilepsy is a heterogeneous complex condition that involve the human brain. Genetic predisposition to epilepsy is a fundamental factor of the disorder aetiology. The sodium voltage-gated channel (SCN) genes variants are critical biomarker… read more here.
Keywords: epilepsy risk; prognosis; sodium voltage; risk ... See more keywords
Complex interactions between p.His558Arg and linked variants in the sodium voltage-gated channel alpha subunit 5 (NaV1.5)
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DOI: 10.7717/peerj.13913
Abstract: Common genetic polymorphisms may modify the phenotypic outcome when co-occurring with a disease-causing variant, and therefore understanding their modulating role in health and disease is of great importance. The polymorphic p.His558Arg variant of the sodium… read more here.
Keywords: voltage gated; sodium voltage; gated channel; alpha subunit ... See more keywords