Real-world effectiveness and safety of sofosbuvir plus daclatasvir with or without ribavirin for genotype 2 chronic hepatitis C in Taiwan.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2018.09.016
Abstract: BACKGROUND AND PURPOSE Sofosbuvir (SOF) and daclatasvir (DCV) treatment achieves excellent efficacy and safety in treating chronic hepatitis C (CHC) with various genotypes. Real world experience of SOF/DCV regimen to treat genotype 2 CHC was… read more here.
Keywords: real world; ribavirin; sof dcv; safety ... See more keywords
Simultaneous quantitation of two direct acting hepatitis C antivirals (sofosbuvir and daclatasvir) by an HPLC‐UV method designated for their pharmacokinetic study in rabbits
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.05.028
Abstract: ABSTRACT Sofosbuvir (SOF) and daclatasvir (DCS) are novel, recently developed direct acting antiviral agents characterized by potent anti‐hepatitis C virus action. A fast and efficient HPLC‐UV method was developed, validated and applied for simultaneous determination… read more here.
Keywords: hepatitis; sofosbuvir daclatasvir; method; sof ... See more keywords
Spectrophotometric and robust UPLC methods for simultaneous determination of velpatasvir and sofosbuvir in their tablet
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DOI: 10.1016/j.microc.2019.103996
Abstract: Abstract Three new methods were developed for the simultaneous determination of velpatasvir (VEL) and sofosbuvir (SOF) in bulk powder and in their pharmaceutical dosage form. Two spectrophotometric methods included first derivative of ratio spectra (1DD)… read more here.
Keywords: simultaneous determination; determination velpatasvir; vel; sof ... See more keywords
The PREVAIL Study: intensive models of HCV care for people who inject drugs
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DOI: 10.1016/s0168-8278(17)30406-3
Abstract: Methods: PREVAIL is a randomized controlled trial that enrolled HCV-infected (genotype 1) PWID maintained on OAT, including those actively using drugs. Participants were randomized to one of three models of HCV care delivered on-site in… read more here.
Keywords: rbv sofosbuvir; prevail study; sof; hcv care ... See more keywords
149 Uptake of C18:0 from culture media during invitro culture decreases cryosurvival rates of bovine embryos
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DOI: 10.1071/rdv33n2ab149
Abstract: Cryosurvival of invitro-produced bovine embryos is lower than that of invivo-produced embryos, limiting their usability in the field. Previous work showed that the embryo’s lipid composition relates to its quality and cryosurvival. The present study… read more here.
Keywords: c18; invitro; cryosurvival; sof ... See more keywords
Comparative Effectiveness of Direct-Acting Antivirals for Posttraumatic Stress Disorder in VA Patients with Hepatitis C Virus Infection.
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DOI: 10.1093/aje/kwac104
Abstract: Our recent exploratory study indicated several direct-acting antivirals (DAAs), highly effective medications for hepatitis C virus (HCV) infection, were also associated with improvement in posttraumatic stress disorder (PTSD) among a national cohort of United States… read more here.
Keywords: sof; acting antivirals; hepatitis virus; gle pib ... See more keywords
Feasible TLC-Spectro-Densitometry Technique for Simultaneous Determination of Two Hepatitis C Antiviral Drugs, Sofosbuvir and Simeprevir: Application to Combined Pharmaceutical Dosage Forms and Human Plasma.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmab034
Abstract: A high-performance thin-layer chromatographic method was developed and validated for the concurrent determination of simeprevir (SMV) and sofosbuvir (SOF). The chromatographic separation was attained on silica gel 60 F254 as stationary phase and ethyl acetate-hexane-methanol… read more here.
Keywords: pharmaceutical dosage; determination; human plasma; sof ... See more keywords
Cost-effectiveness of new antiviral treatments for non-genotype 1 hepatitis C virus infection in China: a societal perspective
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DOI: 10.1136/bmjgh-2020-003194
Abstract: Objective This study aimed to estimate the cost-effectiveness of direct-acting antivirals (DAAs) among patients with non-genotype 1 for the eradication of hepatitis C virus (HCV) infection in China. Methods A decision-analytic Markov model was developed… read more here.
Keywords: non genotype; hepatitis; cost; sof ... See more keywords
Effect of Hemodialysis on Efficacy and Pharmacokinetics of Sofosbuvir Coformulated with Either Daclatasvir or Ledipasvir in Patients with End-Stage Renal Disease
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DOI: 10.1159/000499161
Abstract: Background/Aims: Direct-acting antivirals (DAAs) play a key role in the eradication of hepatitis C virus (HCV) infection. However, limited data are available on DAA for treating HCV infection in hemodialysis (HD) patients. This study was… read more here.
Keywords: hemodialysis; ledipasvir; sof; effect hemodialysis ... See more keywords
Satisfactory virological response and fibrosis improvement of sofosbuvir-based regimens for Chinese patients with hepatitis C virus genotype 3 infection: results of a real-world cohort study
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DOI: 10.1186/s12985-018-1066-8
Abstract: BackgroundChronic hepatitis C virus (HCV) genotype (GT) 3 infection with advanced liver disease has emerged as a challenging to treat by direct-acting antivirals (DAAs), but the efficacy of DAAs in Chinese HCV-GT3 patients is rarely… read more here.
Keywords: sof dcv; infection; sof; study ... See more keywords
Considerations concerning backscattering in the scattering order formulation of the discrete dipole approximation as applied to non-absorbing scatterers.
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DOI: 10.1364/ao.432334
Abstract: The progression of secondary waves emanating from scattering centers within a non-absorbing material in the visible part of the electromagnetic spectrum (wavelength 0.500 µm) is traced using two modeling schemes: the scattering order formulation (SOF)… read more here.
Keywords: approximation; non absorbing; phase function; sof ... See more keywords