Observed Changes in Natural Killer and T cell Phenotypes with Evaluation of Immune Outcome in a Longitudinal Cohort Following Sofosbuvir-Based Therapy for Chronic Hepatitis C Infection
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DOI: 10.1093/ofid/ofz223
Abstract: Abstract Background Chronic hepatitis C virus (HCV) infection diminishes immune function through cell exhaustion and repertoire alteration. Direct acting antiviral (DAA)-based therapy can restore immune cell subset function and reduce exhaustion states. However, the extent… read more here.
Keywords: infection; chronic hepatitis; sofosbuvir based; based therapy ... See more keywords
Use of Sofosbuvir-Based Treatment of Chronic Hepatitis C in Liver Transplant Recipients on Hemodialysis
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DOI: 10.1097/mcg.0000000000000640
Abstract: Background: The use of direct acting agents has changed the management paradigm of hepatitis C (HCV) in liver transplant (LT) recipients. However, the appropriate antiviral regimen in LT recipients on hemodialysis (HD) remains unclear. Methods:… read more here.
Keywords: hepatitis; treatment; hcv; liver transplant ... See more keywords
Sofosbuvir‐based direct acting antiviral therapies for patients with hepatitis C virus genotype 2 infection
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DOI: 10.1111/jgh.14615
Abstract: Data regarding the comparative effectiveness and safety of sofosbuvir (SOF) in combination with ribavirin (RBV), daclatasvir (DCV), or ledipasvir (LDV) for hepatitis C virus genotype 2 (HCV‐2) patients were limited. We aimed to evaluate the… read more here.
Keywords: based direct; direct acting; acting antiviral; hepatitis virus ... See more keywords