Sofosbuvir-Velpatasvir-Voxilaprevir in Adolescents 12 to 17 Years Old With Hepatitis C Virus Infection.
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32393
Abstract: BACKGROUND & AIMS Sofosbuvir-velpatasvir-voxilaprevir is a pangenotypic regimen for chronic hepatitis C virus (HCV) infection. In the United States and Europe, sofosbuvir-velpatasvir-voxilaprevir once daily for 12 weeks is indicated for adults previously receiving an HCV… read more here.
Keywords: infection; velpatasvir voxilaprevir; sofosbuvir velpatasvir; hepatitis virus ... See more keywords
Sofosbuvir/Velpatasvir/Voxilaprevir Versus Sofosbuvir/Velpatasvir Plus Ribavirin in Patients With Hepatitis C Virus Genotype 3b and Compensated Cirrhosis: A Multicentre Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Medical Virology"
DOI: 10.1002/jmv.70709
Abstract: Treatment recommendations for patients with hepatitis C virus (HCV) genotype (GT) 3b infection and cirrhosis remain unclear. This multicentre randomized controlled trial evaluated the efficacy of 12‐week treatment with sofosbuvir/velpatasvir plus ribavirin (arm A) versus… read more here.
Keywords: velpatasvir; compensated cirrhosis; sofosbuvir velpatasvir; arm ... See more keywords
Sofosbuvir-velpatasvir in children 3-17 years old with hepatitis C virus infection.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.12045
Abstract: BACKGROUND The safety and efficacy of sofosbuvir-velpatasvir in children aged 3-17 years with chronic hepatitis C virus (HCV) infection of any genotype were evaluated. METHODS In this Phase 2, multicenter, open-label study, patients received once… read more here.
Keywords: hepatitis virus; sofosbuvir velpatasvir; velpatasvir children; year olds ... See more keywords
Effectiveness and safety of Sofosbuvir/Velpatasvir/Voxilaprevir for retreatment of chronic hepatitis C patients with a previous failure to direct-acting antivirals: a real-life study from the Navigatore Lombardia and Veneto Networks
Sign Up to like & getrecommendations! Published in 2019 at "Digestive and Liver Disease"
DOI: 10.1016/j.dld.2018.11.063
Abstract: Division of Gastroenterology and Hepatology, IRCCS Ospedale Maggiore Policlinico, Milan, Italy [email protected] E. Degasperi1, A. Spinetti2, A. Lombardi3, S. Landonio4, P. G. Scotton5, L. Pasulo6, P. Pozzoni7, A. Giorgini8, P. Fabris9, A. Romano10, L. Lomonaco11,… read more here.
Keywords: effectiveness safety; sofosbuvir velpatasvir; retreatment chronic; voxilaprevir retreatment ... See more keywords
Simplified monitoring of sofosbuvir/velpatasvir in Japanese patients with chronic hepatitis C based on a retrospective analysis of a prospective multicenter cohort
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DOI: 10.1038/s41598-025-26891-4
Abstract: Simplified (“minimal monitoring”) pathways can expand access to direct-acting antivirals (DAAs) by reducing visit burden. In Japan, where hepatitis C virus (HCV) patients are among the oldest worldwide, whether DAA regimens can be delivered safely… read more here.
Keywords: simplified monitoring; sofosbuvir velpatasvir; hepatitis; multicenter cohort ... See more keywords
Bilateral Neuroretinitis Following Treatment with Sofosbuvir and Velpatasvir
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DOI: 10.1080/09273948.2025.2470902
Abstract: ABSTRACT Purpose We report a case of bilateral neuroretinitis like picture following ingestion of Direct Acting Antivirals (DAAs) in the form of sofosbuvir and velpatasvir, for treatment of Chronic Hepatitis C infection. Methods retrospective observational… read more here.
Keywords: treatment; bilateral neuroretinitis; sofosbuvir velpatasvir; following treatment ... See more keywords
Sofosbuvir + velpatasvir + voxilaprevir for the treatment of hepatitis C infection
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DOI: 10.1080/14656566.2018.1459567
Abstract: ABSTRACT Introduction: Hepatitis C is a disease with a significant global impact. Over the last several years, the treatment of the disease has been revolutionized. Therapy has transformed over the last several years with the… read more here.
Keywords: sofosbuvir velpatasvir; hepatitis; treatment; treatment hepatitis ... See more keywords
Safety and efficacy of sofosbuvir-velpatasvir: A meta-analysis
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DOI: 10.1097/md.0000000000031183
Abstract: Introduction: The sofosbuvir-velpatasvir single-tablet regimen (Epclusa) is a newly FDA-approved inhibitor of hepatitis C virus (HCV). This meta-analysis aimed to investigate the safety and efficacy of velpatasvir-sofosbuvir in the treatment of chronic HCV infection. Methods:… read more here.
Keywords: meta; sofosbuvir velpatasvir; meta analysis; safety efficacy ... See more keywords
Eczematous Drug Eruption Induced by Sofosbuvir/Velpatasvir: The Need for a Better Classification.
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Therapeutics"
DOI: 10.1097/mjt.0000000000001071
Abstract: To the Editor: Second-generation direct-acting drugs (DAAs) have revolutionized the treatment of chronic hepatitis C. However, skin-related adverse effects (AEs) have not been properly described and result a common enigma for medical personnel. This is… read more here.
Keywords: sofosbuvir velpatasvir; drug; drug eruption; aes ... See more keywords
Pharmacokinetics of Sofosbuvir/Velpatasvir and efficacy of an alternate‐day treatment in hemodialysis patients with chronic hepatitis C infection
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DOI: 10.1111/cts.13884
Abstract: Sofosbuvir/Velpatasvir (SOF/VEL) is a combination drug used for chronic hepatitis C (HCV) infection. However, limited information exists regarding the pharmacokinetics of SOF/VEL and its metabolites in hemodialysis patients. We conducted a prospective investigation of the… read more here.
Keywords: sof vel; sofosbuvir velpatasvir; hemodialysis patients; efficacy ... See more keywords
A combination of hepatic encephalopathy and body mass index was associated with the point of no return for improving liver functional reserve after sofosbuvir/velpatasvir treatment in patients with hepatitis C virus‐related decompensated cirrhosis
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology Research"
DOI: 10.1111/hepr.13837
Abstract: The real‐world efficacy of sofosbuvir/velpatasvir treatment for patients with hepatitis C virus‐related decompensated cirrhosis is unclear. We aimed to identify factors that improve liver functional reserve after treatment. read more here.
Keywords: velpatasvir treatment; treatment patients; patients hepatitis; hepatitis virus ... See more keywords