Pharmacokinetic and Bioequivalence Study of Eldecalcitol Soft Capsules in Healthy Chinese Subjects
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DOI: 10.1002/cpdd.1159
Abstract: Eldecalcitol is a novel active vitamin D3 1,25(OH)2D3 derivative used in the treatment of osteoporosis. To investigate and compare the pharmacokinetic and bioequivalent profiles of two eldecalcitol soft capsule formulations at a single dose of… read more here.
Keywords: chinese subjects; fed conditions; eldecalcitol soft; soft capsules ... See more keywords
Evaluation of acute and 28-day repeated dose toxicity of Tolypocladium sinense soft capsule in Sprague-Dawley rats
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DOI: 10.1080/01480545.2024.2427766
Abstract: Abstract Tolypocladium sinense is a new asexual strain isolated from natural Cordyceps sinensis. The mycelium produced by its fermentation culture has similar chemical components and pharmacological effects to C. sinensis. T. sinense soft capsule is… read more here.
Keywords: repeated dose; dose toxicity; soft capsules; toxicity ... See more keywords
A Health Technology Assessment Based on Chinese Guideline: Active Vitamin D and Its Analogs in the Treatment of Osteoporosis
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DOI: 10.2147/dddt.s465960
Abstract: Objective To quantitatively assess all dosage forms of three active vitamin D and its analogs, namely, calcitriol, alfacalcidol, and eldecalcitol, to provide a basis for the selection of active vitamin D and its analogs in… read more here.
Keywords: active vitamin; capsules calcitriol; vitamin analogs; soft capsules ... See more keywords
Case report: A case study on the treatment using icaritin soft capsules in combination with lenvatinib achieving impressive PR and stage reduction in unresectable locally progressive pancreatic cancer and a literature review
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1167470
Abstract: Background: Pancreatic cancer is one of the most deadly malignancies in the world. It is characterized by rapid progression and a very poor prognosis. The five-year survival rate of pancreatic cancer in China is only… read more here.
Keywords: pancreatic cancer; case; soft capsules; treatment ... See more keywords
Understanding the Impact of Sustainable Pharmaceutical Packaging on the Chemical Stability of Silodosin
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DOI: 10.3390/pharmaceutics17121548
Abstract: Background/Objectives: Silodosin (SLD) is a selective α1A-adrenoceptor antagonist used in the treatment of benign prostatic hyperplasia. Bioequivalence failures have been reported for hard capsule formulations, largely due to the effect of disintegrant excipients, making soft… read more here.
Keywords: degradation; stability; soft capsules; impurity ... See more keywords