Preservation of the soft protein corona in distinct flow allows identification of weakly bound proteins.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.05.057
Abstract: Nanocarriers that are used for targeted drug delivery come in contact with biological liquids and subsequently proteins will adsorb to the nanocarriers' surface to form the so called 'protein corona'. The protein corona defines the… read more here.
Keywords: corona; soft corona; protein corona; soft protein ... See more keywords
Early Stage Soft Protein Corona Identification on Nanoparticles via Extended Size Exclusion Chromatography.
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DOI: 10.1021/acs.analchem.5c02364
Abstract: Unlike the hard protein corona (HPC), the soft protein corona (SPC) is a dynamic and complex layer for which limited knowledge exists regarding its structure and composition, primarily due to critical challenges in separating and… read more here.
Keywords: protein corona; protein; extended size; soft protein ... See more keywords