Isolation and Identification of 3,4-Seco-Solanidine-3,4-dioic Acid as a Urinary Biomarker of CYP2D6 Activity
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DOI: 10.1124/dmd.122.000957
Abstract: Cytochrome P450 2D6 (CYP2D6) is responsible for the metabolism and elimination of approximately 25% of clinically used drugs, including antidepressants and antipsychotics, and its activity varies considerably on a population basis, primarily because of genetic… read more here.
Keywords: cyp2d6; solanidine; biomarker cyp2d6; activity ... See more keywords