3D printed spherical mini-tablets: Geometry versus composition effects in controlling dissolution from personalised solid dosage forms.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120336
Abstract: Oral dosage forms are by far the most common prescription and over-the-counter pharmaceutical dosage forms used worldwide. However, many patients suffer from adverse effects caused by their use of "one-size fits all" mass produced commercially… read more here.
Keywords: solid dosage; drug; geometry; dosage forms ... See more keywords
Effects of porosity on drug release kinetics of swellable and erodible porous pharmaceutical solid dosage forms fabricated by hot melt droplet deposition 3D printing.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120626
Abstract: 3D printing has the unique ability to produce porous pharmaceutical solid dosage forms on-demand. Although using porosity to alter drug release kinetics has been proposed in the literature, the effects of porosity on the swellable… read more here.
Keywords: porosity; porous pharmaceutical; drug; drug release ... See more keywords
Development of ezetimibe eutectic with improved biopharmaceutical and mechanical properties to design an optimized oral solid dosage formulation
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2143525
Abstract: Abstract Eutectics are multicomponent systems which are an alternative to the conventional techniques for modulating the biopharmaceutical properties of a pharmaceutical. Ezetimibe (ETZ) is a hypocholesterolemic agent with limited dissolution, poor water solubility, and subsequently… read more here.
Keywords: formulation; solid dosage; etz; mechanical properties ... See more keywords
SP0152 3D PRINTED DRUGS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.8556
Abstract: Background: With the advent of personalised medicine, the need for flexible dosing is increasingly important. Conventional pharmaceutical manufacturing processes can be constrained in their ability to offer flexible dosing options to meet patient need. This… read more here.
Keywords: dosage forms; children young; technology; solid dosage ... See more keywords
Investigation of Quantitative X-ray Microscopy for Assessment of API and Excipient Microstructure Evolution in Solid Dosage Processing.
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02271-3
Abstract: Assessment and understanding of changes in particle size of active pharmaceutical ingredients (API) and excipients as a function of solid dosage form processing is an important but under-investigated area that can impact drug product quality.… read more here.
Keywords: microscopy; api; xrm; processing ... See more keywords
Bergamot Essential Oil: A Method for Introducing It in Solid Dosage Forms
Sign Up to like & getrecommendations! Published in 2022 at "Foods"
DOI: 10.3390/foods11233860
Abstract: Bergamot essential oil (BEO) possess antimicrobial, antiproliferative, anti-inflammatory, analgesic, neuroprotective, and cardiovascular effects. However, it is rich in volatile compounds, e.g., limonene, that are susceptible to conversion and degradation reactions. The aim of this communication… read more here.
Keywords: oil; essential oil; bergamot essential; solid dosage ... See more keywords
Microcrystalline Cellulose Extracted from Native Plants as an Excipient for Solid Dosage Formulations in Drug Delivery
Sign Up to like & getrecommendations! Published in 2020 at "Nanomaterials"
DOI: 10.3390/nano10050975
Abstract: Excipients represent the complement of the active principle in any pharmaceutical form. Their function is to provide stability, protection, and to ensure absorption of the drug and acceptability in patients. Cellulose is a conventional excipient… read more here.
Keywords: microcrystalline cellulose; excipient; cellulose; solid dosage ... See more keywords
Development of Advanced 3D-Printed Solid Dosage Pediatric Formulations for HIV Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15040435
Abstract: The combination of lopinavir/ritonavir remains one of the first-line therapies for the initial antiretroviral regimen in pediatric HIV-infected children. However, the implementation of this recommendation has faced many challenges due to cold-chain requirements, high alcohol… read more here.
Keywords: dosage pediatric; printed solid; dosage; advanced printed ... See more keywords
Formulation Strategies to Improve the Stability and Handling of Oral Solid Dosage Forms of Highly Hygroscopic Pharmaceuticals and Nutraceuticals
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102015
Abstract: Highly hygroscopic pharmaceutical and nutraceutical solids are prone to significant changes in their physicochemical properties due to chemical degradation and/or solid-state transition, resulting in adverse effects on their therapeutic performances and shelf life. Moisture absorption… read more here.
Keywords: formulation strategies; highly hygroscopic; solid dosage; hygroscopic pharmaceuticals ... See more keywords
3D Printing Technology as a Promising Tool to Design Nanomedicine-Based Solid Dosage Forms: Contemporary Research and Future Scope
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15051448
Abstract: 3D printing technology in medicine is gaining great attention from researchers since the FDA approved the first 3D-printed tablet (Spritam®) on the market. This technique permits the fabrication of various types of dosage forms with… read more here.
Keywords: nanomedicine based; dosage; solid dosage; printing technology ... See more keywords
Solid Dosage Forms: A Detailed Research on Non-conforming Product Quality
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Pharmaceutical Education and Research"
DOI: 10.5530/ijper.54.3s.146
Abstract: Introduction: Any defects in pharmaceutical products lead to minor, major, or critical deviation and if such a product is released, it also leads to product recalls and legal actions. In such cases, the concern is… read more here.
Keywords: quality; product; dosage forms; solid dosage ... See more keywords