Articles with "solid form" as a keyword



A novel process for preparation of fatty acid oil mixture in solid form.

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Published in 2017 at "Food chemistry"

DOI: 10.1016/j.foodchem.2017.02.055

Abstract: The present study describes a novel and scalable process for preparation of omega-3 and omega-6 fatty acids in solid form. The process involves multiple steps consisting of combining the oil with a metal base in… read more here.

Keywords: solid form; fatty acid; process preparation; form ... See more keywords

Dispensing Small Scale Solids Using Chemical-Coated Beads for Solid Form Screening.

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Published in 2025 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.5c01051

Abstract: Accurate dispensing of small-molecule counterions and coformers is a persistent challenge in solid form screening, particularly for beyond-the-Rule-of-5 (bRo5) drug candidates. In this study, we present the broad applicability of ChemBeads, a coated-bead approach, for… read more here.

Keywords: form screening; solid form; small scale; coated beads ... See more keywords
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Selecting a stable solid form of remdesivir using microcrystal electron diffraction and crystal structure prediction

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Published in 2021 at "RSC Advances"

DOI: 10.1039/d1ra03100g

Abstract: Therapeutic options in response to the coronavirus disease 2019 (COVID-19) outbreak are urgently needed. In this communication, we demonstrate how to support selection of a stable solid form of an antiviral drug remdesivir in quick… read more here.

Keywords: form; solid form; electron diffraction; microcrystal electron ... See more keywords

Controlling polymorphism in molecular cocrystals by variable temperature ball milling.

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Published in 2022 at "Faraday discussions"

DOI: 10.1039/d2fd00115b

Abstract: Mechanochemistry offers a unique opportunity to modify and manipulate crystal forms, often providing new products as compared with conventional solution methods. While promising, there is little known about how to control the solid form through… read more here.

Keywords: polymorphism; solid form; polymorphism molecular; ball milling ... See more keywords