Exploring Solid Forms of Oxytetracycline Hydrochloride.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119496
Abstract: Oxytetracycline hydrochloride, an antibiotic of the tetracycline family, is a polymorphic drug that evidences erratic absorption in oral administration. Additionally, poor solid state characterization of the polymorphs and diversity in the existing nomenclature impede the… read more here.
Keywords: exploring solid; solid forms; spectroscopy; forms oxytetracycline ... See more keywords
Formulation of ionic liquid APIs via spray drying processes to enable conversion into single and two-phase solid forms.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120669
Abstract: Ionic liquid (IL) forms of drugs are increasingly being explored to address problems presented by poorly water-soluble drugs and solid-state stability. However, before ILs of active pharmaceutical ingredients (APIs) can be routinely incorporated into oral… read more here.
Keywords: phase; ionic liquid; two phase; solid forms ... See more keywords
New solid state forms of antineoplastic 5-fluorouracil with anthelmintic piperazine
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.08.076
Abstract: Abstract The aim of the present study was to asses the formation of solid forms between the 5-fluorouracil chemotherapy drug and the anthelmintic piperazine. Two new solid forms of antineoplastic agent 5-fluorouracil with anthelmintic piperazine… read more here.
Keywords: fluorouracil anthelmintic; solid forms; new solid; forms antineoplastic ... See more keywords
Three solid forms of chlorantraniliprole: Structure, characterization, and phase transformation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.06.028
Abstract: Abstract Chlorantraniliprole is one of the most widely used broad-spectrum pesticides. This paper studied three solid forms of chlorantraniliprole, among which two novel solvates were introduced, as well as their crystal structures. Form 2 and… read more here.
Keywords: solid forms; transformation; forms chlorantraniliprole; three solid ... See more keywords
Assembling the Puzzle of Apixaban Solid Forms.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00060
Abstract: An in-depth analysis of the solid forms of the anticoagulant drug Apixaban (APX) has been conducted to sort out the confusion in the scientific and patent literature regarding the solid forms landscape. The nomenclature employed… read more here.
Keywords: apixaban solid; puzzle apixaban; solid forms; assembling puzzle ... See more keywords
Solid forms and β-cyclodextrin complexation of turinabol.
Sign Up to like & getrecommendations! Published in 2022 at "Acta crystallographica. Section C, Structural chemistry"
DOI: 10.1107/s2053229622004004
Abstract: 4-Chloro-17β-hydroxy-17α-methylandrosta-1,4-dien-3-one (C20H27ClO2), known as turinabol, is a synthetic anabolic-androgenic agent which belongs to the steroid class. Recrystallization from various solvents was performed and the following new solid forms of turinabol were obtained: the hemihydrate (C20H27ClO2·0.5H2O),… read more here.
Keywords: cyclodextrin complexation; solid forms; c20h27clo2; forms cyclodextrin ... See more keywords
Multicomponent solid forms of felodipine: preparation, characterisation, physicochemical and in‐vivo studies
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.12685
Abstract: This study aimed to improve biopharmaceutical parameters of the poorly soluble antihypertensive drug, felodipine, by preparing multicomponent solid forms using three coformers, viz. imidazole, nicotinamide and malonic acid. read more here.
Keywords: felodipine preparation; characterisation physicochemical; solid forms; forms felodipine ... See more keywords
Patients’ Preferences and Willingness to Pay for Solid Forms of Oral Medications—Results of the Discrete Choice Experiment in Polish Outpatients
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12030236
Abstract: Purpose: Personal preferences play an important role in the patients’ decision process whether to adhere to treatment, or not. The purpose of this study is to assess Polish outpatients’ preferences for solid forms of oral… read more here.
Keywords: treatment; solid forms; oral medications; polish outpatients ... See more keywords
Virtual Cocrystal Screening of Adefovir Dipivoxyl: Identification of New Solid Forms with Improved Dissolution and Permeation Profiles
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14112310
Abstract: The application of a computational screening methodology based on the calculation of intermolecular interaction energies has guided the discovery of new multicomponent solid forms of the oral antiviral Adefovir Dipivoxyl. Three new cocrystals with resorcinol,… read more here.
Keywords: solid forms; adefovir dipivoxyl; dissolution; improved dissolution ... See more keywords