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1
Published in 2020 at "Drug discovery today"
DOI: 10.1016/j.drudis.2020.12.015
Abstract: The oral sensory perception of medicines is an important quality attribute that can influence adherence to medication. A systematic review identified studies reporting both in vitro and in vivo data on the mouthfeel of solid…
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Keywords:
vitro vivo;
solid oral;
oral dosage;
mouthfeel ... See more keywords
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1
Published in 2017 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.01.014
Abstract: From 2005 to 2014, 370 data entries of dissolution failures of solid oral drug products were assessed with respect to the solubility of drug substances, dosage forms [immediate release (IR) vs. modified release (MR)], and…
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Keywords:
dissolution failure;
oral drug;
solid oral;
drug products ... See more keywords
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Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2018.03.009
Abstract: Literature data relevant to the decision to waive in vivo bioequivalence testing for the approval of generic immediate release solid oral dosage forms of proguanil hydrochloride are reviewed. To elucidate the Biopharmaceutics Classification System (BCS) classification,…
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Keywords:
hydrochloride;
immediate release;
solid oral;
release solid ... See more keywords
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Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.05.019
Abstract: Parameterization of dissolution profiles for subsequent use in in silico modeling and simulation is a crucial element for the success of extrapolating in vitro to in vivo release from solid oral dosage forms. The z-factor…
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Keywords:
solid oral;
oral dosage;
factor;
dosage forms ... See more keywords
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2
Published in 2021 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2021.04.013
Abstract: This review comprehensively summarizes the application of machine learning in solid oral dosage form development over the past three decades. In both academia and industry, machine learning is increasingly applied for multiple preformulation/formulation and process…
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Keywords:
machine;
machine learning;
solid oral;
oral dosage ... See more keywords
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1
Published in 2021 at "Journal of texture studies"
DOI: 10.1111/jtxs.12618
Abstract: Solid Oral Dosage Forms (SODF) are the most popular oral drug delivery forms, but they can be difficult to swallow, especially for patients suffering from swallowing disorders. This study investigated the dynamics of different combinations…
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Keywords:
solid oral;
oral dosage;
rheological properties;
effect ... See more keywords
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Published in 2023 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2023v15i3.47313
Abstract: Designing an appropriate dosage form in medical treatment for the pediatric population is very challenging. The major challenges faced during designing the oral solid dosage form for pediatrics are also the prerequisites for the development…
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Keywords:
formulation;
dosage;
form pediatrics;
solid oral ... See more keywords