Designer Solid Self-Emulsifying Nanovaccines Enable Dual Modulation of Dendritic Cells and T Cells for Potent Antitumor Immunity.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202512139
Abstract: Peptide-based cancer vaccines offer favorable safety and stability profiles but are limited by rapid clearance and poor immunogenicity. Here, a ≈20 nm solid self-emulsifying (SSE) nanovaccine platform that co-delivers peptide antigens and an oligonucleotide adjuvant containing… read more here.
Keywords: designer solid; cells cells; dendritic cells; solid self ... See more keywords
Preparation and evaluation of solid self-microemulsifying drug delivery system of eprosartan mesylate using vegetable oils
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2021.102771
Abstract: Abstract The current work deals with the designing of a solid self-microemulsifying drug delivery system (S-SMEDDS) of eprosartan mesylate (EPM) for improved bioavailability by enhancing the intestinal permeability of EPM. Two L-SMEDDSs containing EPM (OF9… read more here.
Keywords: drug; microemulsifying drug; solid self; drug delivery ... See more keywords
A novel solid self-emulsifying delivery system (SEDS) for the encapsulation of linseed oil and quercetin: Preparation and evaluation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Food Engineering"
DOI: 10.1016/j.jfoodeng.2018.01.017
Abstract: Abstract The aim of current research was to develop a solid self-emulsifying delivery system (SEDS) to enhance the delivery of linseed oil and quercetin. The pseudo ternary phase diagram was constructed to optimize the suitable… read more here.
Keywords: self emulsifying; oil quercetin; linseed oil; solid self ... See more keywords
Development and Optimization of Vitamin D3 Solid Self-Microemulsifying Drug Delivery System: Investigation of Flowability and Shelf Life
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02267-z
Abstract: We report herein the design of a solid self-microemulsifying drug delivery system (SMEDDS) of vitamin D3 for augmentation of its solubility and dissolution. The studies employed a 32 full factorial design by employing JMP 13.2.1,… read more here.
Keywords: vit; solid self; smedds; smedds vit ... See more keywords
Oral pH-Sensitive Solid Self-Microemulsion of Norcantharidin Wrapped in Colon-Coated Capsule for Selective Therapy of Colorectal Carcinoma
Sign Up to like & getrecommendations! Published in 2025 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-025-03056-0
Abstract: Due to the poor solubility, permeability, stability and tumor-targeting ability of norcantharidin (NCTD), currently commercially available NCTD formulations require patients to take the medicine more frequently. Moreover, the formulation of NCTD themselves have certain toxicity,… read more here.
Keywords: wrapped colon; colon coated; colon; self microemulsion ... See more keywords
Solid Self-Nano Emulsifying Nanoplatform Loaded with Tamoxifen and Resveratrol for Treatment of Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14071486
Abstract: The solid self-nanoemulsifying drug delivery system (s-SNEDDS) is a growing platform for the delivery of drugs via oral route. In the present work, tamoxifen (TAM) was loaded in SNEDDS with resveratrol (RES), which is a… read more here.
Keywords: resveratrol; tam res; solid self; breast cancer ... See more keywords
Development of Guar Gum-Pectin-Based Colon Targeted Solid Self-Nanoemulsifying Drug Delivery System of Xanthohumol
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14112384
Abstract: Present study deciphers development of oral polysaccharide-based colon targeted solid self-nanoemulsifying drug delivery system (S-SNEDDS) of xanthohumol (XH). Several studies have shown that XH has anti-inflammatory and antioxidant properties, suggesting that it could be a… read more here.
Keywords: self nanoemulsifying; solid self; colon targeted; targeted solid ... See more keywords
Development of solid self-emulsifying drug delivery systems (SEDDS) to improve the solubility of resveratrol.
Sign Up to like & getrecommendations! Published in 2019 at "Therapeutic delivery"
DOI: 10.4155/tde-2019-0054
Abstract: Aim: A solid self-emulsifying drug delivery systems was developed by using the spray-drying technique, to improve the solubility of resveratrol (RES). Materials & methods: Cod liver oil and three surfactant system were tested: soy phosphatidylcholine… read more here.
Keywords: self emulsifying; solid self; drug delivery; delivery ... See more keywords