Mechanical models and measurement methods of solid stress in tumors
Sign Up to like & getrecommendations! Published in 2024 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-024-13211-5
Abstract: Abstract In addition to genetic mutations, biomechanical factors also affect the structures and functions of the tumors during tumor growth, including solid stress, interstitial fluid pressure, stiffness, and microarchitecture. Solid stress affects tumors by compressing… read more here.
Keywords: models measurement; methods solid; stress; measurement methods ... See more keywords
A comprehensive stress model for gas-particle flows in dense and dilute regimes
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Science"
DOI: 10.1016/j.ces.2020.115833
Abstract: Abstract A comprehensive solid stress model including the whole flow regimes for gas-particle flows is proposed. In the inertial regime characterized by low solid concentrations, solid stress is closed by kinetic theory based on particle… read more here.
Keywords: solid stress; gas particle; model; stress ... See more keywords
Quantifying solid stress and elastic energy from excised or in situ tumors.
Sign Up to like & getrecommendations! Published in 2018 at "Nature protocols"
DOI: 10.1038/nprot.2018.020
Abstract: Solid stress, distinct from both tissue stiffness and fluid pressure, is a mechanical stress that is often elevated in both murine and human tumors. The importance of solid stress in tumor biology has been recognized… read more here.
Keywords: solid stress; stress elastic; elastic energy; stress ... See more keywords
Abstract 3987: Solid stress and elastic energy as measures of tumor mechanopathology
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-3987
Abstract: Introduction: Increased tissue stiffness is a widely accepted and actively studied biomechanical property of desmoplastic tumors, and has been linked to several hallmarks of cancer, such as growth, invasion and metastasis. The abnormal mechanics of… read more here.
Keywords: solid stress; stress elastic; elastic energy; stress ... See more keywords
Abstract 173: Studying the interaction between macrophages and solid stress in novel models of the tumor immune microenvironment
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-173
Abstract: Glioblastoma (GBM) is one of the most aggressive forms of cancer, resisting conventional and immune-based therapies and typically killing patients within two years of diagnosis. This is largely due to the immunosuppressive GBM tumor microenvironment… read more here.
Keywords: studying interaction; macrophages solid; stress; microenvironment ... See more keywords
Abstract 146: Studying the effect of compressive solid stress on macrophage phenotype and function in the context of glioblastoma
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-146
Abstract: Glioblastoma (GBM) is one of the most aggressive forms of brain cancer, with an overall survival of less than two years. One barrier to therapeutic efficacy is the extremely immunosuppressive GBM tumor microenvironment (TME). Myeloid… read more here.
Keywords: macrophage phenotype; stress; tumor; solid stress ... See more keywords
Modeling of the Solid Stress Tensor in the MP-PIC Method: A Review of Methods and Applications
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DOI: 10.3390/math12233700
Abstract: In recent years, the fast growth of computational power has allowed the application of computational fluid dynamics (CFD) in a wide range of areas of interest, such as gas–solid unit operations. In this context, the… read more here.
Keywords: stress tensor; pic method; particle; solid stress ... See more keywords