Synthesis of Chemically Diverse siRNA‐Lipid Conjugates Enabled by Reversible Adsorption to Solid Support (RASS)
Sign Up to like & getrecommendations! Published in 2025 at "ChemBioChem"
DOI: 10.1002/cbic.202500169
Abstract: Small interfering RNAs (siRNAs) directly regulate gene expression and are, thus, attractive targets for clinical development to treat a variety of human diseases. While “naked” siRNAs are poor drug candidates, numerous chemical modifications of siRNAs… read more here.
Keywords: reversible adsorption; solid support; sirna lipid; lipid conjugates ... See more keywords
Sand as a solid support in ultrasound-assisted MSPD: A simple, green and low-cost method for multiresidue pesticide determination in fruits and vegetables.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.05.200
Abstract: Sand was studied as a solid support in ultrasound-assisted matrix solid-phase dispersion (UA-MSPD) for the extraction of different pesticide classes, including organophosphates, carbamates, triazoles and pyrethroids from fruits and vegetables, with determination by GC-MS and… read more here.
Keywords: ultrasound assisted; fruits vegetables; solid support; support ... See more keywords
Influence of Label and Solid Support on the Performance of Heterogeneous Immunoassays.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03543
Abstract: Conventional immunochemical methods used in clinical analysis are often not sensitive enough for early-stage diagnosis, resulting in the need for novel assay formats. Here, we provide a detailed comparison of the effect of different labels… read more here.
Keywords: label solid; heterogeneous immunoassays; solid support; influence label ... See more keywords
Complete Generation of a 129Xe Biosensor on the Solid Support by Systematic Backbone Assembly.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.8b00814
Abstract: Xenon biosensors are an emerging tool for different molecular imaging approaches. For many applications, their development requires peptide synthesis steps, followed by the selective installation of a xenon host onto the peptide backbone in solution.… read more here.
Keywords: biosensor; solid support; biosensor solid; complete generation ... See more keywords
A {Cu6}-added polyoxometalate cluster-organic framework: synthesis, structure and application as a solid support for enzyme immobilization.
Sign Up to like & getrecommendations! Published in 2023 at "Dalton transactions"
DOI: 10.1039/d3dt00822c
Abstract: A new two-dimensional {Cu6}-added polyoxometalate cluster-organic framework (Cu-POMCOF) was prepared by a hydrothermal method from lacunary polyoxoanions and was applied as a solid support for immobilizing MP-11 and Cyt c. The biocomposite complex exhibits higher… read more here.
Keywords: cluster organic; organic framework; polyoxometalate cluster; cu6 added ... See more keywords