Articles with "soloxolone" as a keyword



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Novel Soloxolone Amides as Potent Anti-Glioblastoma Candidates: Design, Synthesis, In Silico Analysis and Biological Activities In Vitro and In Vivo

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Published in 2022 at "Pharmaceuticals"

DOI: 10.3390/ph15050603

Abstract: The modification of natural or semisynthetic triterpenoids with amines can be explored as a promising strategy for improving their pharmacological properties. Here, we report the design and synthesis of 11 novel amide derivatives of soloxolone… read more here.

Keywords: design synthesis; glioblastoma; soloxolone; anti glioblastoma ... See more keywords