Effect of optimization methods on Hansen solubility ellipsoids
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.44621
Abstract: In Hansen solubility parameters (HSPs) space, the solubility region of a solute is modeled as an axis-aligned ellipsoid, of which Hansen sphere is a special case. The solubility ellipsoids of six materials are determined by… read more here.
Keywords: optimization methods; hansen solubility; solubility; solubility ellipsoids ... See more keywords
Synthesis and in vitro assessment of novel water‐soluble dextran‐docetaxel conjugates as potential pH sensitive system for tumor‐targeted delivery
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.45457
Abstract: Docetaxel is a potent taxane agent mostly used in breast, lung, and prostate cancers. Its low water solubility is the major drawback that leads to use of Tween 80 as surfactant and ethanol as solvent… read more here.
Keywords: water; dextran; solubility; targeted delivery ... See more keywords
Enhancing biosynthesis of 2'‐Fucosyllactose in Escherichia coli through engineering lactose operon for lactose transport and α ‐1,2‐Fucosyltransferase for solubility
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28048
Abstract: 2'‐Fucosyllactose (2'‐FL) is the most abundant oligosaccharide in human milk and one of the most actively studied human milk oligosaccharides (HMOs). When 2'‐FL is produced through biological production using a microorganism, like Escherichia coli, d‐lactose… read more here.
Keywords: operon; lactose transport; escherichia coli; solubility ... See more keywords
Accurate model based on artificial intelligence for prediction of carbon dioxide solubility in aqueous tetra‐n‐butylammonium bromide solutions
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Chemometrics"
DOI: 10.1002/cem.2956
Abstract: This study highlights the application of radial basis function (RBF) neural networks, adaptive neuro‐fuzzy inference systems (ANFIS), and gene expression programming (GEP) in the estimation of solubility of CO2 in aqueous solutions of tetra‐n‐butylammonium bromide… read more here.
Keywords: prediction; butylammonium bromide; tetra butylammonium; solubility ... See more keywords
Modeling of Hansen's solubility parameters of aripiprazole, ziprasidone, and their impurities: A nonparametric comparison of models for prediction of drug absorption sites
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Chemometrics"
DOI: 10.1002/cem.2996
Abstract: Aripiprazole and ziprasidone are atypical antipsychotic drugs with the effect on positive and negative symptoms of schizophrenia, mania, and mixed states of bipolar disorder. Hansen's solubility parameters, δd, δp, and δh, which account for dispersive,… read more here.
Keywords: aripiprazole ziprasidone; absorption sites; hansen solubility; solubility ... See more keywords
Polysubstituted Pyrimidines as Potent Inhibitors of Prostaglandin E2 Production: Increasing Aqueous Solubility
Sign Up to like & getrecommendations! Published in 2021 at "ChemMedChem"
DOI: 10.1002/cmdc.202100263
Abstract: Water solubility is one of the key features of potential therapeutic agents. In order to enhance the low water solubility of the parent 5‐butyl‐4‐(4‐methoxyphenyl)‐6‐phenylpyrimidin‐2‐amine, a potent inhibitor of prostaglandin E2 (PGE2) production, we synthesized and… read more here.
Keywords: production; water solubility; solubility; parent ... See more keywords
Enhanced Solubility and Reduced Crystallinity of Carotenoids, β‐Carotene and Astaxanthin, by Z‐Isomerization
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DOI: 10.1002/ejlt.201800191
Abstract: The impact of the Z‐isomer content of carotenoids, β‐carotene and astaxanthin, on their solubility in organic solvents and crystallinity is investigated. Carotenoid samples containing different Z‐isomer contents are prepared from the high‐purity all‐E‐isomers by the… read more here.
Keywords: crystallinity; isomer; isomerization; carotenoids carotene ... See more keywords
DMSO tolerant NAD(P)H recycler enzyme from a pathogenic bacterium, Burkholderia dolosa PC543: effect of N‐/C‐terminal His Tag extension on protein solubility and activity
Sign Up to like & getrecommendations! Published in 2018 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201800036
Abstract: NAD(P)+ dependent formate dehydrogenase (FDH) is an oxidoreductase used as a biocatalyst to regenerate NAD(P)H in reductase‐mediated chiral synthesis reactions. Solvent stability and the need to reduce NADP+ to NADPH, due to the high cost… read more here.
Keywords: solubility activity; dmso tolerant; enzyme; solubility ... See more keywords
Captisol®: an efficient carrier and solubilizing agent for essential oils and their components
Sign Up to like & getrecommendations! Published in 2017 at "Flavour and Fragrance Journal"
DOI: 10.1002/ffj.3395
Abstract: Essential oils (EOs) and their individual components have several biological properties and are used in cosmetics, food and pharmaceutical industries. However, their application still presents a challenge owing mainly to their volatility and their poor… read more here.
Keywords: aqueous solubility; captisol efficient; carrier; solubility ... See more keywords
Ultrasonic depolymerization of aqueous tara gum solutions: kinetic, thermodynamic and physicochemical properties.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11824
Abstract: BACKGROUND Tara gum is characterized by its high viscosity and medium solubility, which is due to its high molecular mass. However, for many applications, these characteristics are undesirable and make their use infeasible. The present… read more here.
Keywords: depolymerization aqueous; solubility; tara gum; tara ... See more keywords
Phosphorylated walnut protein isolate as a nanocarrier for enhanced water solubility and stability of curcumin.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11917
Abstract: BACKGROUND The low solubility and poor dispersion of alkaline-extracted walnut protein isolate (AWPI) limit its application as a protein-based carrier for the delivery of poorly soluble nutraceuticals, including curcumin. This work investigated the physicochemical characteristics… read more here.
Keywords: protein isolate; curcumin; walnut protein; solubility ... See more keywords