Solubility and isoelectric point of cefradine in different solvent systems
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DOI: 10.1016/j.molliq.2019.112312
Abstract: Abstract The solubility data of cefradine in different solvent systems as a function of pH were determined by dynamic method. The effect of pH and solvent compositions on the solubility data and the isoelectric points… read more here.
Keywords: solubility data; solubility; solvent systems; different solvent ... See more keywords
Solubility and thermodynamic mixing and dissolution properties of empagliflozin in pure and binary solvent systems
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.113004
Abstract: Abstract In this work, the solubility data of empagliflozin in nine pure solvents and one binary solvent were measured by dynamic method at the temperature ranging from 278.15 K to 313.15 K. The results showed that the… read more here.
Keywords: solubility data; solvent systems; model; solubility ... See more keywords
Some comments concerning “Measurement and correlation of solubility data for atorvastatin calcium in pure and binary solvent systems from 293.15 K to 328.15 K”
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DOI: 10.1016/j.molliq.2021.116066
Abstract: Abstract The reported solubility data of atorvastatin calcium in binary aqueous mixtures of acetone at various temperatures from 293.15 K to 328.15 K was reanalyzed based on some well-established cosolvency models and a number of… read more here.
Keywords: 293 328; comments concerning; atorvastatin calcium; solubility data ... See more keywords
Comment on the Importance of Documenting Drug Solubility Measurement Methodology, Including Characterizing the Physical Form of the Solute, for Meaningful Understanding, Interpretation, and Reporting of Solubility Data
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DOI: 10.14227/dt260419p6
Abstract: T his commentary continues the discussion initiated in a previous article entitled “Comment on the Importance of Data Transparency, Openness, and Reproducibility in Dissolution Science and Technology” (1). As a follow-up, this commentary more specifically… read more here.
Keywords: methodology; solubility data; comment importance; documenting drug ... See more keywords
Application of COSMO-RS-DARE as a Tool for Testing Consistency of Solubility Data: Case of Coumarin in Neat Alcohols
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DOI: 10.3390/molecules27165274
Abstract: Coumarin is a naturally occurring lactone-type benzopyrone with various applications in the pharmaceutical, food, perfume, and cosmetics industries. This hydrophobic compound is poorly soluble in water but dissolves well in protic organic solvents such as… read more here.
Keywords: consistency; solubility; solubility data; coumarin ... See more keywords