Methacrylate-copolymer Eudragit EPO as solubility-enabling excipient for anionic drugs: Investigation of drug solubility, intestinal permeability, and their interplay.
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DOI: 10.1021/acs.molpharmaceut.9b00057
Abstract: The purpose of this work was to investigate the use of the dimethylaminoethyl methacrylate-copolymer Eudragit EPO (EPO) in oral solubility- enabling formulations for anionic lipophilic drugs, aiming to guide optional formulation design, and maximize oral… read more here.
Keywords: solubility enabling; methacrylate copolymer; permeability; drug ... See more keywords