Estimation of critical point, vapor pressure and heat of sublimation of pharmaceuticals and their solubility in supercritical carbon dioxide
Sign Up to like & getrecommendations! Published in 2019 at "Fluid Phase Equilibria"
DOI: 10.1016/j.fluid.2019.01.020
Abstract: Abstract The critical point and vapor pressure of pharmaceuticals are required in the calculation of their solubility in supercritical fluids by using an equation of state. The experimental critical point of many pharmaceuticals are not… read more here.
Keywords: solubility supercritical; critical point; point vapor; vapor pressure ... See more keywords
Thermodynamic modelling and experimental validation of pharmaceutical solubility in supercritical solvent
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.114120
Abstract: Abstract Particle size and morphology are among the most important parameters which must be precisely controlled in pharmaceutical industries to enhance the effectiveness of the solid dosage oral formulations. One of the most interesting methods… read more here.
Keywords: pressure; temperature; solubility; solubility supercritical ... See more keywords
Phosphatidylcholine solubility in supercritical carbon dioxide: Experimental data, thermodynamic modeling, and application in bioactive-encapsulated liposome synthesis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Supercritical Fluids"
DOI: 10.1016/j.supflu.2019.104720
Abstract: Abstract The solubility of phosphatidylcholine (PC) in supercritical-CO2 (SC-CO2) was measured experimentally using a dynamic system for the pressure and temperature range of 12.4–17.2 MPa and 313−353 K, respectively. The data were used to model the solubility… read more here.
Keywords: phosphatidylcholine solubility; supercritical carbon; experimental data; carbon dioxide ... See more keywords
Penicillins’ Solubility in Supercritical Carbon Dioxide: Modeling by Cubic Equations of States Revisited
Sign Up to like & getrecommendations! Published in 2021 at "Antibiotics"
DOI: 10.3390/antibiotics10121448
Abstract: Development of processes using green solvents as supercritical fluids (SCFs) depends on the accuracy of modeling and predicting phase equilibrium which is of considerable importance to exploit the use of SCF process at the level… read more here.
Keywords: supercritical carbon; sublimation pressure; cubic equations; penicillins solubility ... See more keywords