A Novel Soluble ACE2 Protein Provides Lung and Kidney Protection in Mice Susceptible to Lethal SARS-CoV-2 Infection.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2021091209
Abstract: Background: Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) uses full-length angiotensin converting enzyme 2 (ACE2) as a main receptor to enter target cells. The goal of this study was to demonstrate the preclinical efficacy… read more here.
Keywords: novel soluble; ace2 protein; soluble ace2; sars cov ... See more keywords
Soluble ACE2 and TMPRSS2 Levels in the Serum of Asthmatic Patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Korean Medical Science"
DOI: 10.3346/jkms.2022.37.e65
Abstract: Background Angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine subtype 2 (TMPRSS2) are key proteins mediating viral entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although gene expressions of ACE2 and TMPRSS2 have been… read more here.
Keywords: levels serum; asthmatic patients; soluble ace2; tmprss2 levels ... See more keywords
Engineered soluble ACE2 receptor: Responding to change with change
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1084331
Abstract: SARS coronavirus 2 (SARS-CoV-2) invades the human body by binding to major receptors such as ACE2 via its S-spike protein, so the interaction of receptor-binding sites has been a hot topic in the development of… read more here.
Keywords: engineered soluble; change; soluble ace2; ace2 receptor ... See more keywords
Circulating Soluble ACE2 Plays an Independent Role to Protect against Vascular Damage in Diabetic Mice
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DOI: 10.3390/antiox11050987
Abstract: Circulating levels of soluble ACE2 are increased by diabetes. Although this increase is associated with the presence and severity of cardiovascular disease, the specific role of soluble ACE2 in atherogenesis is unclear. Previous studies suggested… read more here.
Keywords: ace2; circulating soluble; role; soluble ace2 ... See more keywords