Predictive value of soluble fms‐like tyrosine kinase‐1 against placental growth factor for preeclampsia in a Chinese pregnant women population
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22861
Abstract: The purpose of the present study was to explore the predictive effects of soluble fms‐like tyrosine kinase‐1 (sFlt‐1) and placental growth factor (PlGF) for preeclampsia. read more here.
Keywords: fms like; like tyrosine; placental growth; growth factor ... See more keywords
Real-world data on the clinical use of angiogenic factors in pregnancies with placental dysfunction.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of obstetrics and gynecology"
DOI: 10.1016/j.ajog.2020.10.028
Abstract: BACKGROUND In routine clinical practice, angiogenic factor measurement can facilitate prediction and diagnosis of preeclampsia and other manifestations of placental dysfunction (eg, intrauterine growth restriction). OBJECTIVE This real-world data analysis investigated the utility of soluble… read more here.
Keywords: like tyrosine; soluble fms; factor; growth ... See more keywords
Soluble FMS-Like Tyrosine Kinase-1 Is a Circulating Biomarker Associated With Calcific Aortic Stenosis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2019.01.020
Abstract: Calcific aortic stenosis (CAS) is the end manifestation of calcific aortic valve disease (CAVD). There are no medical therapies to reverse or slow the progression of CAVD [(1)][1]. Circulating biomarkers may provide insights into CAVD… read more here.
Keywords: like tyrosine; aortic stenosis; soluble fms; calcific aortic ... See more keywords
Placental Growth Factor and Soluble, Fms-Like Tyrosine Kinase-1 in Preeclampsia: A Case-Cohort (PEARL) Study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC"
DOI: 10.1016/j.jogc.2020.03.024
Abstract: OBJECTIVE Preeclampsia is associated with a higher maternal blood levels of soluble fms-like tyrosine kinase-1 (sFlt-1) and lower levels of placental growth factor (PlGF) that appear before clinical onset. We aimed to estimate the normal… read more here.
Keywords: like tyrosine; cohort; soluble fms; preeclampsia ... See more keywords
Upregulation and release of soluble fms‐like tyrosine kinase receptor 1 mediated by complement activation in human syncytiotrophoblast cells
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13033
Abstract: Antiangiogenic molecule soluble fms‐like tyrosine kinase receptor 1 (sFLT1) released from trophoblast cells is associated with pregnancy‐specific hypertensive disorder pre‐eclampsia. Cause of elevated sFLT1 in pre‐eclampsia patients is not well understood. Despite evidence of excess… read more here.
Keywords: like tyrosine; soluble fms; activation; complement activation ... See more keywords
Activating Transcription Factor 3 Is Reduced in Preeclamptic Placentas and Negatively Regulates sFlt-1 (Soluble fms-Like Tyrosine Kinase 1), Soluble Endoglin, and Proinflammatory Cytokines in Placenta
Sign Up to like & getrecommendations! Published in 2017 at "Hypertension"
DOI: 10.1161/hypertensionaha.117.09548
Abstract: Preeclampsia is a major pregnancy complication associated with poor placental perfusion and placental hypoxia. Systemic and placental inflammation and elevated placental secretion of the antiangiogenic factors sFlt-1 (soluble fms-like tyrosine kinase 1) and sEng (soluble… read more here.
Keywords: preeclamptic placentas; atf3; soluble fms; factor ... See more keywords
Sleep disordered breathing controlled by CPAP and sFlt-1 in a pregnant patient with chronic hypertension: Case report and literature review
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DOI: 10.1177/1753495x17708949
Abstract: Background There is recent interest exploring the possible impact of sleep disordered breathing on the mechanisms of preeclampsia. A biomarker of preeclampsia, soluble fms-like tyrosine kinase-1, has come to prominence in recent years. The aim… read more here.
Keywords: sleep disordered; like tyrosine; soluble fms; disordered breathing ... See more keywords
Circulating soluble fms-like tyrosine kinase-1 and placental growth factor from 10 to 40 weeks’ pregnancy in normotensive women
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DOI: 10.1515/jpm-2017-0093
Abstract: Abstract Introduction: Circulating soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) are potential markers for preeclampsia. The objective was to construct and analyse the reference ranges of serum levels of sFlt-1 and PlGF… read more here.
Keywords: pregnancy; circulating soluble; plgf; sflt plgf ... See more keywords
Value of soluble fms-like tyrosine kinase-1/placental growth factor test in third trimester of pregnancy for predicting preeclampsia in asymptomatic women
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DOI: 10.1515/jpm-2022-0127
Abstract: Abstract Objectives To estimate the value of screening maternal serum soluble fms-like tyrosine kinase/placental growth factor (sFlt-1/PlGF) ratio in asymptomatic women during 3rd trimester to predict preeclampsia (PE) development. Methods The investigated group comprised of… read more here.
Keywords: soluble fms; like tyrosine; test; tyrosine kinase ... See more keywords
Circulating Soluble Fms-Like Tyrosine Kinase in Renal Diseases Other Than Preeclampsia.
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DOI: 10.1681/asn.2020111579
Abstract: Soluble Fms-like tyrosine kinase (sFlt-1/sVEGFR1) is a natural occurring antagonist of vascular endothelial growth factor (VEGF). Despite being a secreted, soluble protein lacking cytoplasmic and transmembrane domains, sFlt-1 can act locally and be protective against… read more here.
Keywords: tyrosine kinase; like tyrosine; diseases preeclampsia; soluble fms ... See more keywords
The VEGF Inhibitor Soluble Fms-like Tyrosine Kinase 1 Does Not Promote AKI-to-CKD Transition
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DOI: 10.3390/ijms23179660
Abstract: (1) Background: Soluble Fms-like tyrosine kinase 1 (sFLT1) is an endogenous VEGF inhibitor. sFLT1 has been described as an anti-inflammatory treatment for diabetic nephropathy and heart fibrosis. However, sFLT1 has also been related to peritubular… read more here.
Keywords: soluble fms; like tyrosine; sflt1; tyrosine kinase ... See more keywords