Soluble forms of cytokine and growth factor receptors: mechanisms of generation and modes of action in the regulation of local and systemic inflammation
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DOI: 10.1002/1873-3468.14305
Abstract: Cytokine and growth factor receptors are usually transmembrane proteins, but they can also exist in soluble forms, either through cleavage and release of their ligand‐binding extracellular domain or through the secretion of a soluble isoform.… read more here.
Keywords: factor receptors; cytokine growth; soluble forms; growth factor ... See more keywords
Abstract 5540: Clinical significance of soluble forms of immune checkpoint molecules in advanced esophageal cancer
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DOI: 10.1158/1538-7445.am2018-5540
Abstract: Background: Immune checkpoint molecules such as PDL1 and CD155 are expressed on cancer cells and regulate tumor immunity by binding to ligands on immune cells. Although soluble forms of immune checkpoint molecules have been detected… read more here.
Keywords: esophageal cancer; immune checkpoint; checkpoint molecules; advanced esophageal ... See more keywords
Do Changes in ACE-2 Expression Affect SARS-CoV-2 Virulence and Related Complications: A Closer Look into Membrane-Bound and Soluble Forms
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DOI: 10.3390/ijms22136703
Abstract: The SARS-CoV-2 virus utilizes angiotensin converting enzyme (ACE-2) for cell entry and infection. This enzyme has important functions in the renin-angiotensin aldosterone system to preserve cardiovascular function. In addition to the heart, it is expressed… read more here.
Keywords: membrane bound; bound soluble; soluble forms; expression ... See more keywords
Design and Investigation of New Water-Soluble Forms of α-Tocopherol with Antioxidant and Antiglycation Activity Using Amphiphilic Copolymers of N-Vinylpyrrolidone
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DOI: 10.3390/pharmaceutics15051388
Abstract: Water-soluble forms of α-tocopherol (TP) as an effective antioxidant were obtained by encapsulating it into nanoparticles (NPs) of amphiphilic copolymers of N-vinylpyrrolidone with triethylene glycol dimethacrylate (CPL1-TP) and N-vinylpyrrolidone with hexyl methacrylate and triethylene glycol… read more here.
Keywords: antiglycation activity; soluble forms; activity; water soluble ... See more keywords