Differential Pattern of Soluble Immune Markers in Asymptomatic Dengue, West Nile and Zika Virus Infections
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DOI: 10.1038/s41598-019-53645-w
Abstract: Infections with dengue virus (DENV), West Nile virus (WNV) and Zika virus (ZIKV) usually present similar mild symptoms at early stages, and most infections (~80%) are asymptomatic. However, these infections may progress to severe disease… read more here.
Keywords: immune markers; soluble immune; wnv; west nile ... See more keywords
Clinical significance of circulating soluble immune checkpoint proteins in sorafenib-treated patients with advanced hepatocellular carcinoma
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DOI: 10.1038/s41598-020-60440-5
Abstract: In hepatocellular carcinoma (HCC), the clinical significance of soluble immune checkpoint protein levels as predictors of patient outcomes or therapeutic responses has yet to be defined. This study profiled the baseline levels of sixteen soluble… read more here.
Keywords: hepatocellular carcinoma; checkpoint proteins; soluble immune; checkpoint ... See more keywords
Association of baseline soluble immune checkpoints with the risk of relapse in PR3-ANCA vasculitis following induction of remission
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DOI: 10.1136/ard-2022-222479
Abstract: Objectives We investigated whether soluble immune checkpoints (sICPs) predict treatment resistance, relapse and infections in patients with antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV). Methods Plasma sICP concentrations from available samples obtained during conduct of the… read more here.
Keywords: baseline; anca vasculitis; vasculitis; remission ... See more keywords
Soluble immune checkpoints in cancer: production, function and biological significance
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DOI: 10.1186/s40425-018-0449-0
Abstract: Immune checkpoints play important roles in immune regulation, and blocking immune checkpoints on the cell membrane is a promising strategy in the treatment of cancer. Based on this, monoclonal antibodies are having much rapid development,… read more here.
Keywords: production; biological significance; soluble immune; cancer ... See more keywords
Soluble immune checkpoint-related proteins as predictors of tumor recurrence, survival, and T cell phenotypes in clear cell renal cell carcinoma patients
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DOI: 10.1186/s40425-019-0810-y
Abstract: BackgroundImmune checkpoint inhibitors have achieved unprecedented success in cancer immunotherapy. With the exception of a few candidate biomarkers, the prognostic role of soluble immune checkpoint-related proteins in clear cell renal cell cancer (ccRCC) patients is… read more here.
Keywords: immune checkpoint; recurrence; related proteins; checkpoint related ... See more keywords
A Soluble Immune Effector Binds Both Fungi and Bacteria via Separate Functional Domains
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DOI: 10.3389/fimmu.2019.00369
Abstract: The gut microbiome of animals consists of diverse microorganisms that include both prokaryotes and eukaryotes. Complex interactions occur among these inhabitants, as well as with the immune system of the host, and profoundly influence the… read more here.
Keywords: binds fungi; fungi bacteria; immune effector; soluble immune ... See more keywords
Editorial: Regulation of Soluble Immune Mediators by Non-Coding RNAs
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DOI: 10.3389/fimmu.2020.607222
Abstract: Non-coding RNAs (ncRNAs), defined as transcripts that do not encode proteins, are known since long time for their role in translation (i.e. transfer RNAs, ribosomal RNAs) and in splicing events (i.e. small nuclear and small… read more here.
Keywords: coding rnas; soluble immune; non coding; editorial regulation ... See more keywords
Soluble Immune-Related Proteins as New Candidate Serum Biomarkers for the Diagnosis and Progression of Lymphangioleiomyomatosis
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DOI: 10.3389/fimmu.2022.844914
Abstract: Background The goal of this study was to analyze serum from lymphangioleiomyomatosis (LAM) patients and healthy controls to identify novel biomarkers that could shed light on disease diagnosis and pathogenesis. Methods From April 2017 to… read more here.
Keywords: lymphangioleiomyomatosis; serum; candidate serum; lam patients ... See more keywords
Soluble Immune Checkpoint-Related Proteins in Blood Are Associated With Invasion and Progression in Non-Small Cell Lung Cancer
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DOI: 10.3389/fimmu.2022.887916
Abstract: Background Immune checkpoint inhibition therapy has been achieved significant success in the treatment of non-small cell lung cancer (NSCLC). However, the role of soluble immune checkpoint- related proteins in NSCLC remains obscure. Methods We evaluated… read more here.
Keywords: cancer; immune checkpoint; related proteins; checkpoint ... See more keywords
Unravelling soluble immune checkpoints in chronic lymphocytic leukemia: Physiological immunomodulators or immune dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.965905
Abstract: Chronic lymphocytic leukemia (CLL) is a lymphoid neoplasm characterized by the accumulation of mature B cells. The diagnosis is established by the detection of monoclonal B lymphocytes in peripheral blood, even in early stages [monoclonal… read more here.
Keywords: lymphocytic leukemia; immune checkpoints; dysfunction; chronic lymphocytic ... See more keywords
Prediction of risk and overall survival of pancreatic cancer from blood soluble immune checkpoint-related proteins
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DOI: 10.3389/fimmu.2023.1189161
Abstract: Background Immune checkpoint inhibition holds promise as a novel treatment for pancreatic ductal adenocarcinoma (PDAC). The clinical significance of soluble immune checkpoint (ICK) related proteins have not yet fully explored in PDAC. Methods We comprehensively… read more here.
Keywords: immune checkpoint; related proteins; pdac patients; subtype ... See more keywords