Hiding in Plain Sight: Soluble Immunomodulatory Receptors.
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DOI: 10.1016/j.it.2018.08.004
Abstract: Alternatively spliced natural soluble isoforms of immunomodulatory receptors [cytotoxic T lymphocyte antigen-4 (CTLA-4), 4-1BB, and programmed death-1 (PD-1)/PD-L1] have been overlooked in favor of their cell-surface-bound counterparts that have generated blockbuster antibodies for the treatment… read more here.
Keywords: immunomodulatory receptors; sight soluble; hiding plain; plain sight ... See more keywords