Lower circulating soluble Klotho level is associated with increased risk of all-cause mortality in chronic kidney disease patients: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "International Urology and Nephrology"
DOI: 10.1007/s11255-020-02510-1
Abstract: Purpose This study aimed to investigate the association between circulating soluble Klotho level and risk of all-cause mortality in chronic kidney disease (CKD) patients using systematic review and meta-analysis technique. Methods Potentially eligible studies were… read more here.
Keywords: risk; circulating soluble; lower circulating; klotho level ... See more keywords
Soluble klotho as an effective biomarker to characterize inflammatory states
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DOI: 10.1080/07853890.2022.2077428
Abstract: Abstract Background & Aims Soluble α-Klotho (s-Klotho) is a circulating protein with pleiotropic effects that mainly induce protective effects. Our study investigates the associations between s-Klotho and several established inflammatory biomarkers, with the aim of… read more here.
Keywords: inflammatory biomarkers; biomarker; inflammatory states; klotho ... See more keywords
The association of soluble Klotho levels with anemia and hemoglobin variability in hemodialysis patients
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DOI: 10.1111/sdi.13122
Abstract: The anti‐aging protein Klotho levels are decreased, and Klotho deficiency is associated with cardiovascular diseases in patients with chronic kidney disease. There are recent studies about the relation between soluble Klotho levels and anemia. We… read more here.
Keywords: hemoglobin variability; klotho; anemia hemoglobin; soluble klotho ... See more keywords
Composite Dietary Antioxidant Index and Plasma Levels of Soluble Klotho: Insights from NHANES
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DOI: 10.1155/2023/3524611
Abstract: Objectives The association between dietary antioxidants and soluble Klotho (S-Klotho) levels remains unknown. We investigated to explore whether the composite dietary antioxidant index (CDAI) was associated with serum levels of S-Klotho in the middle-aged population.… read more here.
Keywords: index; klotho; plasma; composite dietary ... See more keywords
Shedding of Klotho: Functional Implications in Chronic Kidney Disease and Associated Vascular Disease
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DOI: 10.3389/fcvm.2020.617842
Abstract: α-Klotho (Klotho) exists in two different forms, a membrane-bound and soluble form, which are highly expressed in the kidney. Both forms play an important role in various physiological and pathophysiological processes. Recently, it has been… read more here.
Keywords: shedding klotho; kidney disease; disease; soluble klotho ... See more keywords
Does Dapagliflozin influence arterial stiffness and levels of circulating anti-aging hormone soluble Klotho in people with type 2 diabetes and kidney disease? Results of a randomized parallel group clinical trial
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.992327
Abstract: Objective The mechanisms that explain the cardio-renal benefits of sodium glucose co-transporter 2 (SGLT-2) inhibitors are unknown. The effect of SGLT-2 inhibitors on arterial aging, measured by Aortic Pulse Wave Velocity (Ao-PWV) and Soluble Klotho… read more here.
Keywords: anti aging; people type; arterial aging; klotho ... See more keywords
Association between Soluble α-Klotho Protein and Metabolic Syndrome in the Adult Population
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DOI: 10.3390/biom12010070
Abstract: Klotho protein is an anti-aging protein and plays multiple roles in ion-regulation, anti-oxidative stress, and energy metabolism through various pathways. Metabolic syndrome is a combination of multiple conditions that compose of multiple risk factors of… read more here.
Keywords: metabolic syndrome; soluble klotho; klotho protein; protein ... See more keywords