Serum-soluble (pro)renin receptor concentration as a biomarker for organ damage in primary aldosteronism
Sign Up to like & getrecommendations! Published in 2019 at "Hypertension Research"
DOI: 10.1038/s41440-019-0312-9
Abstract: Primary aldosteronism is characterized by inappropriate overproduction of aldosterone by adrenal lesions and leads to hypertension. Excess aldosterone causes organ damage; therefore, finding a biomarker for organ damage risk is vital. The (pro)renin receptor regulates… read more here.
Keywords: renin; renin receptor; organ damage; pro renin ... See more keywords
Soluble (pro)renin receptor level in patients with severe obesity is associated with visceral adiposity and is involved with insulin resistance and renal injury.
Sign Up to like & getrecommendations! Published in 2023 at "Obesity facts"
DOI: 10.1159/000531076
Abstract: INTRODUCTION High soluble (pro)renin receptor (s(P)RR) level in circulation is reported in obese patients; however, it is unclear which body composition components are responsible for it. In this study, the authors examined blood s(P)RR levels… read more here.
Keywords: soluble pro; renin receptor; receptor level; level ... See more keywords
The relationship between kidney function and the soluble (pro)renin receptor in young adults: the African-PREDICT study
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DOI: 10.1186/s12882-025-04038-x
Abstract: High renin angiotensin-aldosterone system (RAAS) activity is associated with target organ damage. Soluble (pro)renin receptor [s(P)RR] forms part of the RAAS cascade and is associated with kidney damage through both angiotensin II-dependent and -independent pathways.… read more here.
Keywords: soluble pro; kidney function; renin; study ... See more keywords
Soluble (Pro)Renin Receptor Levels Are Regulated by Plasma Renin Activity and Correlated with Edema in Mice and Humans with HFrEF
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DOI: 10.3390/biomedicines10081874
Abstract: Symptomatic heart failure with reduced ejection fraction (HFrEF) is characterized by edema and chronic pathological activation of the classical renin–angiotensin–aldosterone system (RAAS). The soluble (pro)renin receptor (s(P)RR) is released into circulation by proteolytic cleavage of… read more here.
Keywords: soluble pro; renin receptor; dysfunction; renin ... See more keywords