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Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep39884
Abstract: Uric acid is a damage-associated molecular pattern (DAMP), released from ischemic tissues and dying cells which, when crystalized, is able to activate the NLRP3 inflammasome. Soluble uric acid (sUA) is found in high concentrations in…
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Keywords:
nlrp3 inflammasome;
uric acid;
activates nlrp3;
soluble uric ... See more keywords
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Published in 2017 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000366
Abstract: Purpose of review Gout is a common debilitating form of arthritis and despite our extensive knowledge on the pathogenesis its prevalence is still rising quickly. In the current review, we provide a concise overview of…
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Keywords:
gouty;
inflammatory response;
soluble uric;
gout ... See more keywords
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Published in 2020 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2020.44948.10482
Abstract: Objective(s): Hyperuricemia is a risk for cardiovascular and metabolic diseases, but the mechanism is ambiguous. Increased intestinal permeability is correlated with metabolic syndrome risk factors. Intestinal epithelial cells play a pivotal role in maintaining intestinal…
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Keywords:
uric acid;
intestinal epithelial;
epithelial cells;
soluble uric ... See more keywords