Pterostilbene-Loaded Soluplus/Poloxamer 188 Mixed Micelles for Protection against Acetaminophen-Induced Acute Liver Injury.
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DOI: 10.1021/acs.molpharmaceut.2c00881
Abstract: Excessive acetaminophen (APAP) induces excess reactive oxygen species (ROS), leading to liver damage. Pterostilbene (PTE) has excellent antioxidant and anti-inflammatory activities, but poor solubility limits its biological activity. In this study, we prepared PTE-loaded Soluplus/poloxamer… read more here.
Keywords: liver injury; soluplus poloxamer; poloxamer 188; apap induced ... See more keywords