Loss of aquaporin-4 impairs cerebrospinal fluid solute clearance through cerebrospinal fluid drainage pathways
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-79147-y
Abstract: The aquaporin-4 (AQP4) water channel is essential in neurofluid dynamics. AQP4 loss impairs solute exchange between the cerebrospinal fluid (CSF) and interstitial fluid (ISF). However, whether AQP4 expression affects solute clearance from the CSF space… read more here.
Keywords: solute clearance; cerebrospinal fluid; drainage pathways; csf ... See more keywords
tubular secretory solute clearance and hiv infection.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of acquired immune deficiency syndromes"
DOI: 10.1097/qai.0000000000003200
Abstract: BACKGROUND Tubular secretion is an important kidney function responsible for the clearance ofnumerous medications including antibiotics and antivirals. It is unknown whether or not persons living with HIV have lower secretion compared with HIV-uninfected persons,… read more here.
Keywords: clearance; without hiv; hiv; solute clearance ... See more keywords
Moving beyond small solute clearance: What evidence is there for more permeable dialyzers and haemodiafiltration?
Sign Up to like & getrecommendations! Published in 2018 at "Hemodialysis International"
DOI: 10.1111/hdi.12700
Abstract: Dialyzers were initially developed for diffusive clearance of uraemic toxins. Diffusion most effectively clears small uncharged solutes from plasma water, such as urea. Sessional urea clearance targets have been shown to be important for short‐term… read more here.
Keywords: solute clearance; patient survival; middle sized; clearance ... See more keywords
Mapping Solute Clearance From the Mouse Hippocampus Using a 3D Imaging Cryomicrotome
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.631325
Abstract: The hippocampus is susceptible to protein aggregation in neurodegenerative diseases such as Alzheimer’s disease. This protein accumulation is partially attributed to an impaired clearance; however, the removal pathways for fluids and waste products are not… read more here.
Keywords: solute clearance; hippocampus; mapping solute; clearance mouse ... See more keywords