A practical solution to pseudoreplication bias in single-cell studies.
Sign Up to like & getrecommendations! Published in 2021 at "Nature communications"
DOI: 10.1038/s41467-021-21038-1
Abstract: Cells from the same individual share common genetic and environmental backgrounds and are not statistically independent; therefore, they are subsamples or pseudoreplicates. Thus, single-cell data have a hierarchical structure that many current single-cell methods do… read more here.
Keywords: single cell; bias single; solution pseudoreplication; practical solution ... See more keywords