Articles with "solvent gradient" as a keyword



Enrichment of Full AAV2 Using Multicolumn Countercurrent Solvent Gradient Purification (MCSGP)

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Published in 2025 at "Biotechnology and Bioengineering"

DOI: 10.1002/bit.29036

Abstract: Adeno‐associated viruses (AAVs) are non‐pathogenic viruses that have become promising delivery vehicles in cell and gene therapy, with several AAV‐based therapeutics receiving approval in recent years. However, a critical challenge is the separation of full… read more here.

Keywords: purification; multicolumn countercurrent; solvent gradient; countercurrent solvent ... See more keywords

End group Functionality of 95 to 99%: Epoxide Functionalization of Polystyryl-Lithium Evaluated via Solvent Gradient Interaction Chromatography (SGIC).

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Published in 2022 at "Macromolecular rapid communications"

DOI: 10.1002/marc.202200560

Abstract: End group functionality is a key parameter of functional polymer chains. The end-capping efficiency of living polystyryl lithium with various epoxides, namely ethylene oxide (EO), ethoxy ethyl glycidyl ether (EEGE) and isopropylidene glyceryl glycidyl ether… read more here.

Keywords: solvent gradient; group functionality; group; end group ... See more keywords