Solvent Sites Improve Docking Performance of Protein-Protein Complexes and Protein-Protein Interface-Targeted Drugs
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DOI: 10.1021/acs.jcim.2c00264
Abstract: Protein-protein interactions (PPIs) are essential, and modulating their function through PPI-targeted drugs is an important research field. PPI sites are shallow protein surfaces readily accessible to the solvent, thus lacking a proper pocket to fit… read more here.
Keywords: targeted drugs; protein protein; ppi; solvent sites ... See more keywords