Getting “Ras”-ults: Solving Molecular Promiscuity through Microdomain-Selective Targeting
Sign Up to like & getrecommendations! Published in 2018 at "Neuron"
DOI: 10.1016/j.neuron.2018.05.001
Abstract: In this issue of Neuron, Zhang et al. (2018) report a powerful new method for probing subcellular microdomain-specific signaling in cellular function. Through a microdomain-targeting approach, they delineate how Ras-family GTPases balance signaling diversity with specificity… read more here.
Keywords: ults solving; molecular promiscuity; ras ults; solving molecular ... See more keywords
Solving molecular compounds from powder diffraction data: are results always reliable?
Sign Up to like & getrecommendations! Published in 2022 at "IUCrJ"
DOI: 10.1107/s2052252522006571
Abstract: Commentary is given on a paper [Schlesinger et al. (2022). IUCrJ, 9, 406–424.] reporting on ambiguous structure determination from powder data using four different structural models of 4,11-difluoroquinacridone with similar X-ray powder patterns. read more here.
Keywords: diffraction data; compounds powder; molecular compounds; powder diffraction ... See more keywords
Solving the Molecular Basis of the Developmental and Epileptic Encephalopathies: Are We there Yet?
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsy Currents"
DOI: 10.1177/15357597211038180
Abstract: Objective: To assess the benefits and limitations of whole genome sequencing (WGS) compared to exome sequencing (ES) or multigene panel (MGP) in the molecular diagnosis of developmental and epileptic encephalopathies (DEEs). Methods: We performed WGS… read more here.
Keywords: epileptic encephalopathies; solving molecular; structural variants; complex structural ... See more keywords