The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19221-x
Abstract: The ASCC3 subunit of the activating signal co-integrator complex is a dual-cassette Ski2-like nucleic acid helicase that provides single-stranded DNA for alkylation damage repair by the α-ketoglutarate-dependent dioxygenase AlkBH3. Other ASCC components integrate ASCC3/AlkBH3 into… read more here.
Keywords: cancer mutations; affected somatic; dna repair; ascc2 ascc3 ... See more keywords
A clinical research on the potential pathogenesis of somatic cancer related cerebral venous sinus thrombosis
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000015134
Abstract: Abstract To investigate the pathogenesis of somatic solid cancer-related cerebral venous sinus thrombosis (CVST). A total of 174 patients with CVST were recruited from the hospital between January 2006 and December 2017 and divided into… read more here.
Keywords: somatic cancer; cancer; group patients; cancer related ... See more keywords