SOMATIC DRIVER MUTATIONS IN ORAL AND SINONASAL MUCOSAL MELANOMA. A REFERRAL CENTRE EXPERIENCE IN MEXICO CITY
Sign Up to like & getrecommendations! Published in 2019 at "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"
DOI: 10.1016/j.oooo.2019.02.199
Abstract: Objective Oral and sinonasal mucosal melanomas (OSNMM) are aggressive tumors with low survival and few therapeutic alternatives. The aim of this study was to describe the prevalence of mutations in NRASQ61K, BRAFV600E, CKITL576P, K642E, MITFE318K… read more here.
Keywords: mexico city; oral sinonasal; pathology; somatic driver ... See more keywords
Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-26489-0
Abstract: Driver gene mutations that are more prevalent in metastatic, castration-resistant prostate cancer (mCRPC) than localized disease represent candidate prognostic biomarkers. We analyze 1,844 localized (1,289) or mCRPC (555) tumors and quantify the prevalence of 113… read more here.
Keywords: prostate; loss predictor; somatic driver; znrf3 loss ... See more keywords