The somatic molecular evolution of cancer: Mutation, selection, and epistasis.
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DOI: 10.1016/j.pbiomolbio.2021.08.003
Abstract: Cancer progression has been attributed to somatic changes in single-nucleotide variants, copy-number aberrations, loss of heterozygosity, chromosomal instability, epistatic interactions, and the tumor microenvironment. It is not entirely clear which of these changes are essential… read more here.
Keywords: evolution; somatic molecular; biology; cancer ... See more keywords