Spectrum of abnormalities and clonal transformation in germline RUNX1 familial platelet disorder and a genomic comparative analysis with somatic RUNX1 mutations in MDS/MPN overlap neoplasms
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DOI: 10.1038/s41375-020-0752-x
Abstract: The Runt-related transcription factor 1 (RUNX1) gene encodes a transcription factor that plays a crucial role in embryogenesis and definitive hematopoiesis [1]. Germline RUNX1 mutations (RUNX1) result in a familial platelet disorder with propensity to… read more here.
Keywords: germline runx1; somatic runx1; runx1; mpn overlap ... See more keywords