Darwinian selection within an individual or somatic selection: facts and models
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DOI: 10.1093/jmcb/mjz014
Abstract: There are known cases where a cell subpopulation bearing a selective advantage tends to or eventually replaces another cell subpopulation within an organism. This process is supposed to underlie the purging of the most frequent… read more here.
Keywords: darwinian selection; selection within; somatic selection; selection ... See more keywords
Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers
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DOI: 10.1158/0008-5472.can-21-0086
Abstract: The genetic determinants of the somatic mutational processes in cancer elucidate the biology underlying somatic selection and evolution of cancers and demonstrate complementary predictive power across cancer types. The somatic landscape of the cancer genome… read more here.
Keywords: biology; cancer; somatic selection; genetic determinants ... See more keywords