Noonan syndrome‐associated myeloproliferative disorder with somatically acquired monosomy 7: impact on clinical decision making
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DOI: 10.1111/bjh.16191
Abstract: Haematological manifestations in Noonan syndrome (NS), the most common RASopathy, encompass a broad phenotypic spectrum ranging from transient monocytosis, thrombocytopenia to myeloproliferative disorder (MPD) (Roberts et al, 2013). In the majority of patients, NS-MPD is… read more here.
Keywords: methylation; somatically acquired; noonan syndrome; jmml ... See more keywords
Abstract B24: Characterization of somatically acquired regulatory mutations in high-risk neuroblastoma
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.pedca17-b24
Abstract: Neuroblastoma is a childhood cancer of the developing peripheral nervous system and is uniquely characterized by a broad spectrum of phenotypes ranging from spontaneous tumor regression to relentless progression. The 5-year survival rate for children… read more here.
Keywords: risk; somatically acquired; characterization somatically; high risk ... See more keywords