Altered biomass allocation and quality improvement in roots of Indian ginseng Withania somnifera Dunal. Linn. through physiological interventions
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DOI: 10.1016/j.heliyon.2020.e05093
Abstract: Ashwagandha (W. somnifera Dunal. Linn.), known as Indian ginseng, contains three major bioactive compounds, withaferin-A (WA), 12-deoxywithastramonolide (WO) and withanoloide A (WD). In a field experiment, the impacts of foliar application of growth retardants/promoters was… read more here.
Keywords: foliar application; biomass; indian ginseng; dunal linn ... See more keywords
Up-regulation of Squalene synthase in hairy root culture of Withania somnifera (L.) Dunal yields higher quantities of withanolides
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DOI: 10.1016/j.indcrop.2020.112706
Abstract: Abstract The roots of Indian ginseng, Withania somnifera (L.) Dunal (Solanaceae) are extensively used in ayurvedic and other traditional medicines. The plant produces a steroidal lactone, withanolide which has multiple health benefits. Squalene synthase plays… read more here.
Keywords: withania somnifera; squalene synthase; somnifera dunal; synthase ... See more keywords
Withania somnifera (L.) Dunal: A potential therapeutic adjuvant in cancer.
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DOI: 10.1016/j.jep.2020.112759
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Withania somnifera (L.) Dunal (WS) is one of the most-studied Rasayana botanicals used in Ayurveda practice for its immunomodulatory, anti-aging, adaptogenic, and rejuvenating effects. The botanical is being used for various clinical indications,… read more here.
Keywords: withania somnifera; therapeutic adjuvant; molecular mechanisms; cancer ... See more keywords
Pharmacological potential of Withania somnifera (L.) Dunal and Tinospora cordifolia (Willd.) Miers on the experimental models of COVID-19, T cell differentiation, and neutrophil functions
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DOI: 10.3389/fimmu.2023.1138215
Abstract: Cytokine release syndrome (CRS) due to severe acute respiratory coronavirus-2 (SARS-CoV-2) infection leads to life-threatening pneumonia which has been associated with coronavirus disease (COVID-19) pathologies. Centuries-old Asian traditional medicines such as Withania somnifera (L.) Dunal… read more here.
Keywords: tinospora cordifolia; withania somnifera; dunal tinospora; willd miers ... See more keywords
Withania somnifera (L.) Dunal (Ashwagandha); current understanding and future prospect as a potential drug candidate
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DOI: 10.3389/fphar.2022.1029123
Abstract: Cancer and Neurodegenerative diseases are one of the most dreadful diseases to cure and chemotherapy has found a prime place in cancerous treatments while as different strategies have been tested in neurodegenerative diseases as well.… read more here.
Keywords: ashwagandha current; withania somnifera; dunal ashwagandha; somnifera ... See more keywords
An updated review on phytochemistry and molecular targets of Withania somnifera (L.) Dunal (Ashwagandha)
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DOI: 10.3389/fphar.2023.1049334
Abstract: Withania somnifera (L.) Dunal belongs to the nightshade family Solanaceae and is commonly known as Ashwagandha. It is pharmacologically a significant medicinal plant of the Indian sub-continent, used in Ayurvedic and indigenous systems of medicine… read more here.
Keywords: withania somnifera; ashwagandha; updated review; molecular targets ... See more keywords
Differential Gene Expression and Withanolides Biosynthesis During in vitro and ex vitro Growth of Withania somnifera (L.) Dunal
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DOI: 10.3389/fpls.2022.917770
Abstract: Ashwagandha (Withania somnifera L. Dunal) is a medicinally important plant with withanolides as its major bioactive compounds, abundant in the roots and leaves. We examined the influence of plant growth regulators (PGRs) on direct organogenesis,… read more here.
Keywords: vitro vitro; growth; withania somnifera; expression ... See more keywords
Withaferin A: A Pleiotropic Anticancer Agent from the Indian Medicinal Plant Withania somnifera (L.) Dunal
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DOI: 10.3390/ph16020160
Abstract: Cancer represents the second most deadly disease and one of the most important public health concerns worldwide. Surgery, chemotherapy, radiation therapy, and immune therapy are the major types of treatment strategies that have been implemented… read more here.
Keywords: indian medicinal; cancer; withania somnifera; plant withania ... See more keywords