MicroRNA-23b-3p participates in steroid-induced osteonecrosis of the femoral head by suppressing ZNF667 expression
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DOI: 10.1016/j.steroids.2020.108709
Abstract: BACKGROUND Clinical treatment with high-dose of steroid hormone causes steroid-induced osteonecrosis of the femoral head (SONFH), whereas the internal regulation mechanism remains elusive. Numerous studies have reported that microRNAs participated in the development of SONFH… read more here.
Keywords: znf667; mir 23b; steroid induced; expression ... See more keywords
Association between genetic polymorphisms and osteonecrosis in steroid treatment populations: a detailed stratified and dose-response meta-analysis
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DOI: 10.1042/bsr20190024
Abstract: Steroid treatment has become recognized as an important risk factor for avascular osteonecrosis of the femoral head. However, not all patients who receive long-term, high-dose steroids develop osteonecrosis, indicating that there are individual differences in… read more here.
Keywords: treatment; risk; prednisone use; osteonecrosis ... See more keywords
Identification of Inflammation-Related Genes and Exploration of Regulatory Mechanisms in Patients with Osteonecrosis of the Femoral Head
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DOI: 10.1155/2022/4501186
Abstract: Background Osteonecrosis of the femoral head (ONFH) is a disabling orthopedic disease, which is impacted by infiltration of immune cells. Thus, the aim of the current research was to determine the inflammation-related biomarkers in ONFH.… read more here.
Keywords: femoral head; inflammation; sonfh; inflammation related ... See more keywords
Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head
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DOI: 10.3390/ijms231911275
Abstract: As a widely used steroid hormone medicine, glucocorticoids have the potential to cause steroid-induced osteonecrosis of the femoral head (SONFH) due to mass or long-term use. The non-coding RNA hypothesis posits that they may contribute… read more here.
Keywords: steroid; induced osteonecrosis; apoptosis; sonfh ... See more keywords