Activatable Cancer Sono‐Immunotherapy using Semiconducting Polymer Nanobodies
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202203246
Abstract: Despite the great promises of sonodynamic therapy (SDT) in combination cancer therapy, its clinical applications are hindered by the “always‐on” pharmacological activities of therapeutic agents and the lack of efficient sonosensitizers. Herein, the development of… read more here.
Keywords: using semiconducting; immunotherapy; sono immunotherapy; activatable cancer ... See more keywords
Ultrasound-Activated PROTAC Prodrugs Overcome Immunosuppression to Actuate Efficient Deep-Tissue Sono-Immunotherapy in Orthotopic Pancreatic Tumor Mouse Models.
Sign Up to like & getrecommendations! Published in 2024 at "Nano letters"
DOI: 10.1021/acs.nanolett.4c02287
Abstract: The degradation of oncoproteins mediated by proteolysis-targeting chimera (PROTAC) has emerged as a potent strategy in cancer therapy. However, the clinical application of PROTACs is hampered by challenges such as poor water solubility and off-target… read more here.
Keywords: sono immunotherapy; deep tissue; mouse; orthotopic ... See more keywords