In Vitro Sonothrombolysis Enhancement by Transiently Stable Microbubbles Produced by a Flow-Focusing Microfluidic Device
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-017-1965-7
Abstract: Therapeutic approaches that enhance thrombolysis by combining recombinant tissue plasminogen activator (rtPA), ultrasound, and/or microbubbles (MBs) are known as sonothrombolysis techniques. To date, sonothrombolysis approaches have primarily utilized commercially available MB formulations (or derivatives thereof)… read more here.
Keywords: sonothrombolysis; vitro sonothrombolysis; microfluidic device; focusing microfluidic ... See more keywords
Efficacy of Sonothrombolysis Using Microbubbles Produced by a Catheter-Based Microfluidic Device in a Rat Model of Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-019-02209-0
Abstract: Limitations of existing thrombolytic therapies for acute ischemic stroke have motivated the development of catheter-based approaches that utilize no or low doses of thrombolytic drugs combined with a mechanical action to either dissolve or extract… read more here.
Keywords: catheter; sonothrombolysis; ischemic stroke; catheter based ... See more keywords
Efficacy and safety of sonothrombolysis in patients with acute ischemic stroke: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2020.116998
Abstract: BACKGROUND Accumulating clinical evidence has indicated that sonothrombolysis can aid in the treatment of ischemic stroke; however, these findings remain controversial. The purpose of the present meta-analysis was to assess randomized clinical studies concerning the… read more here.
Keywords: ischemic stroke; sonothrombolysis; safety; efficacy ... See more keywords
Contrast enhanced sonothrombolysis using streptokinase loaded phase change nano-droplets for potential treatment of deep venous thrombosis
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DOI: 10.1039/d2ra04467f
Abstract: Current thrombolytic therapies for deep venous thrombosis are limited due to the wide side effect profile. Contrast mediated sonothrombolysis is a promising approach for thrombus treatment. The current study examines the effectiveness of in vitro… read more here.
Keywords: deep venous; venous thrombosis; mediated sonothrombolysis; sonothrombolysis ... See more keywords
A Model of High-Speed Endovascular Sonothrombolysis with Vortex Ultrasound-Induced Shear Stress to Treat Cerebral Venous Sinus Thrombosis
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DOI: 10.1101/2022.11.02.514936
Abstract: This research aims to demonstrate a novel vortex ultrasound enabled endovascular thrombolysis method designed for treating cerebral venous sinus thrombosis (CVST). This is a topic of significant importance since current treatment modalities for CVST still… read more here.
Keywords: vortex ultrasound; cerebral venous; ultrasound; sonothrombolysis ... See more keywords
Sonothrombolysis Promotes Improvement in Left Ventricular Wall Motion and Perfusion Scores after Acute Myocardial Infarction.
Sign Up to like & getrecommendations! Published in 2022 at "Arquivos brasileiros de cardiologia"
DOI: 10.36660/abc.20200651
Abstract: BACKGROUND It has recently been demonstrated that the application of high-energy ultrasound and microbubbles, in a technique known as sonothrombolysis, dissolves intravascular thrombi and increases the angiographic recanalization rate in patients with ST-segment-elevation myocardial infarction… read more here.
Keywords: sonothrombolysis; myocardial infarction; perfusion; wall motion ... See more keywords
Sonothrombolysis for acute ischemic stroke - Break on through to the other side
Sign Up to like & getrecommendations! Published in 2017 at "Neurology India"
DOI: 10.4103/0028-3886.198213
Abstract: Background: Intravenous (IV) tissue plasminogen activator (tPA) infusion combined with transcranial low-frequency ultrasound waves targeted on the occluded arterial segment (sonothrombolysis) can increase recanalization in large artery-acute ischemic stroke (LA-AIS). Aims: To evaluate the benefits… read more here.
Keywords: ischemic stroke; sonothrombolysis; sonothrombolysis acute; time ... See more keywords