Changes in plasma interleukin-8 and tumor necrosis factor-α levels during the early treatment period as a predictor of the response to sorafenib in patients with unresectable hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3681-x
Abstract: PurposeThis study aimed to identify a biomarker for predicting the response to sorafenib in patients with hepatocellular carcinoma (HCC).MethodsOf 100 patients with unresectable HCC who received sorafenib treatment in our institute (Cohort A), 48 had… read more here.
Keywords: response; treatment; cohort; response sorafenib ... See more keywords
Pharmacokinetics and pharmacogenetics of sorafenib in patients with hepatocellular carcinoma: Implications for combination trials
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DOI: 10.1111/liv.14587
Abstract: Sorafenib and lenvatinib are the first‐line treatments approved in hepatocellular carcinoma (HCC), but information is lacking about the relationships between their pharmacokinetics, patients pharmacogenetic profiles, adverse events (AE) and overall survival. We aimed to elucidate… read more here.
Keywords: hepatocellular carcinoma; combination; pharmacokinetics pharmacogenetics; pharmacogenetics sorafenib ... See more keywords
Randomized phase II trial of sorafenib, capecitabine and oxaliplatin (SECOX) versus single agent sorafenib in patients with advanced hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.365
Abstract: 365 Background: We aimed to compare the efficacy and tolerability of SECOX regimen with sorafenib alone as first-line treatment of advanced hepatocellular cancer (HCC) in a multicenter, open-label and randomized setting. Methods: Patients not suitable… read more here.
Keywords: advanced hepatocellular; sorafenib patients; capecitabine; mos ... See more keywords
Corrigendum: Real-World Lenvatinib Versus Sorafenib in Patients With Advanced Hepatocellular Carcinoma: A Propensity Score Matching Analysis
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DOI: 10.3389/fonc.2021.823960
Abstract: [This corrects the article DOI: 10.3389/fonc.2021.737767.]. read more here.
Keywords: corrigendum real; lenvatinib versus; versus sorafenib; world lenvatinib ... See more keywords