Sortase A-Generated Highly Potent Anti-CD20-MMAE Conjugates for Efficient Elimination of B-Lineage Lymphomas.
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DOI: 10.1002/smll.201602267
Abstract: Antibody-drug conjugate (ADC) targeting antigens expressed on the surface of tumor cells are an effective approach for delivering drugs into the cells via antigen-mediated endocytosis. One of the well-known tumor antigens, the CD20 of B-lymphocyte,… read more here.
Keywords: sortase generated; lineage lymphomas; ofa vcmmae; anti cd20 ... See more keywords