Endocytic sorting and downregulation of the M2 acetylcholine receptor is regulated by ubiquitin and the ESCRT complex
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DOI: 10.1016/j.neuropharm.2019.107828
Abstract: Cholinergic dysfunction plays a critical role in a number of disease states, and the loss of functional muscarinic acetylcholine receptors plays a key role in disease pathogenesis. Therefore, preventing receptor downregulation would maintain functional receptor… read more here.
Keywords: sorting downregulation; acetylcholine; endocytic sorting; muscarinic receptor ... See more keywords