Articles with "sost" as a keyword



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Thirty days of spaceflight does not alter murine calvariae structure despite increased Sost expression☆

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Published in 2017 at "Bone Reports"

DOI: 10.1016/j.bonr.2017.08.004

Abstract: Previously our laboratory documented increases in calvaria bone volume and thickness in mice exposed to 15 days of spaceflight aboard the NASA Shuttle mission STS-131. However, the tissues were not processed for gene expression studies… read more here.

Keywords: sost; calvaria bone; bone; expression ... See more keywords
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Common and rare variants of WNT16, DKK1 and SOST and their relationship with bone mineral density

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-29242-8

Abstract: Numerous GWAS and candidate gene studies have highlighted the role of the Wnt pathway in bone biology. Our objective has been to study in detail the allelic architecture of three Wnt pathway genes: WNT16, DKK1… read more here.

Keywords: wnt16 dkk1; bone mineral; sost; dkk1 sost ... See more keywords
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Effects of periodontal and bisphosphonate treatment on the gingival crevicular levels of sclerostin and dickkopf-1 in postmenopausal osteoporosis with and without periodontitis.

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Published in 2022 at "Journal of periodontal research"

DOI: 10.1111/jre.13023

Abstract: OBJECTIVE AND BACKGROUND Both periodontitis and osteoporosis are associated with osteoclast-related bone resorption. Bone metabolism is regulated by wingless-type MMTV integration site family (WNT), and WNT/β-catenin signals are controlled by physiological antagonists including dickkopf-1 (DKK-1)… read more here.

Keywords: dickkopf; sost; osteoporosis; group ... See more keywords
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Relationship Between Sclerostin (SOST) Expression and Genetic Loci rs851056, rs1230399 Polymorphisms and Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes in Xinjiang

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Published in 2021 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"

DOI: 10.2147/dmso.s305831

Abstract: Background The Wnt signaling pathway plays a valuable role in bone metabolism. SOST is a major inhibitor of the Wnt signaling pathway. The expression of SOST and genetic polymorphism might be associated with bone mineral… read more here.

Keywords: expression; sost; bone mineral; postmenopausal women ... See more keywords
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Investigation of the Underlying Mechanism of Sclerosteosis Expression in Muscle Tissue in Multiple Myeloma with Sarcopenia

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Published in 2023 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s391465

Abstract: Objective To explore the role of sclerosteosis (SOST) gene expression in the occurrence and development of multiple myeloma (MM) complicated with sarcopenia. Methods Analysis of the SOST expression in skeletal muscle tissue of patients with… read more here.

Keywords: sost; myeloma; muscle; expression ... See more keywords
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Knockdown of POSTN Inhibits Osteogenic Differentiation of Mesenchymal Stem Cells From Patients With Steroid-Induced Osteonecrosis

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Published in 2020 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2020.606289

Abstract: Steroid-induced osteonecrosis of femoral head (SONFH) is a common and serious complication caused by long-term and/or excessive use of glucocorticoids (GCs). The decreased activity and abnormal differentiation of bone marrow mesenchymal stem cells (BMSCs) are… read more here.

Keywords: sost; postn; expression; differentiation ... See more keywords
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The Influence of Epigallocatechin Gallate on the Nuclear Factor Associated T Cell-1 and Sclerostin Expression in Wistar Rats (Rattus novergicus) during the Orthodontic Tooth Movement

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Published in 2020 at "Research Journal of Pharmacy and Technology"

DOI: 10.5958/0974-360x.2020.00312.1

Abstract: Orthodontic tooth movement is obtained through alveolar bone remodeling and periodontal tissue in response to the mechanical forces. Epigallocatechin Gallate (EGCG) is the most abundant bioactive component in green tea which is promising therapy for… read more here.

Keywords: sost; tooth movement; group; expression ... See more keywords
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Enhanced Serum miR-153-3p Promotes the Development of Knee Osteoarthritis by Targeting SOST.

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Published in 2020 at "Clinical laboratory"

DOI: 10.7754/clin.lab.2020.200223

Abstract: BACKGROUND The current study aims to identify the expression of serum miR-153-3p in knee osteoarthritis (KOA) patients, thereby evaluating its diagnostic value in clinic. METHODS The KOA group was divided into mild group, moderate group,… read more here.

Keywords: group; mir 153; sost; serum mir ... See more keywords